脊髓灰质炎病毒感染的现状
Current status of poliovirus infections.
作者信息
Melnick J L
机构信息
Division of Molecular Virology, Baylor College of Medicine, Houston, Texas 77030, USA.
出版信息
Clin Microbiol Rev. 1996 Jul;9(3):293-300. doi: 10.1128/CMR.9.3.293.
Abstract
Two scientists who played leading roles in the conquest of poliomyelitis died recently. In 1954, Jonas Salk provided the first licensed polio vaccine, the formalin (and heat)-inactivated virus. Albert Sabin gave us the attenuated live virus vaccine, which was licensed in 1962. This paper takes the reader through the history of the disease, including its pathogenesis, epidemiology, vaccines, and future directions. The emphasis is on vaccines, for it seems that with proper vaccination the number of new cases is falling dramatically. It is hoped that by the year 2000, we will accomplish the goal of the World Health Organization of "a world without polio." Then, because there is no animal reservoir, we can seriously discuss when and how to eliminate the need for vaccination and ultimately destroy our stocks of poliovirus.
摘要
两位在征服脊髓灰质炎过程中发挥了主导作用的科学家最近去世了。1954年，乔纳斯·索尔克提供了第一种获得许可的脊髓灰质炎疫苗，即福尔马林（和加热）灭活病毒疫苗。阿尔伯特·萨宾为我们带来了减毒活病毒疫苗，该疫苗于1962年获得许可。本文带领读者回顾了这种疾病的历史，包括其发病机制、流行病学、疫苗以及未来发展方向。重点是疫苗，因为似乎通过适当的疫苗接种，新病例的数量正在急剧下降。人们希望到2000年，我们能够实现世界卫生组织“一个没有脊髓灰质炎的世界”的目标。然后，由于没有动物储存宿主，我们可以认真讨论何时以及如何消除疫苗接种的必要性，并最终销毁我们的脊髓灰质炎病毒储备。
相似文献
1
Current status of poliovirus infections.脊髓灰质炎病毒感染的现状
Clin Microbiol Rev. 1996 Jul;9(3):293-300. doi: 10.1128/CMR.9.3.293.
2
An Introduction to Poliovirus: Pathogenesis, Vaccination, and the Endgame for Global Eradication.脊髓灰质炎病毒简介：发病机制、疫苗接种及全球根除的最终目标
Methods Mol Biol. 2016;1387:1-10. doi: 10.1007/978-1-4939-3292-4_1.
3
The fight against poliomyelitis through the history: past, present and hopes for the future. Albert Sabin's missing Nobel and his "gift to all the world's children".通过历史抗击脊髓灰质炎：过去、现在和未来的希望。阿尔伯特·萨宾（Albert Sabin）错失的诺贝尔奖及其“送给全世界儿童的礼物”。
Vaccine. 2022 Nov 8;40(47):6802-6805. doi: 10.1016/j.vaccine.2022.09.088. Epub 2022 Oct 14.
4
[Worldwide eradication of poliomyelitis].全球消灭脊髓灰质炎
Wien Klin Wochenschr. 2001 Oct 30;113(20-21):839-45.
5
Sequential inactivated (IPV) and live oral (OPV) poliovirus vaccines for preventing poliomyelitis.用于预防脊髓灰质炎的序贯灭活脊髓灰质炎疫苗（IPV）和口服脊髓灰质炎减毒活疫苗（OPV）
Cochrane Database Syst Rev. 2019 Dec 5;12(12):CD011260. doi: 10.1002/14651858.CD011260.pub2.
6
[100 years of studying poliomyelitis virus and nonpoliomyelitis enteroviruses].[研究脊髓灰质炎病毒和非脊髓灰质炎肠道病毒的百年历程]
Vopr Virusol. 2008 Jul-Aug;53(4):41-4.
7
Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis.与使用减毒活疫苗脊灰病毒株相关的风险，以及控制和消灭麻痹性脊髓灰质炎的策略。
Expert Rev Vaccines. 2012 May;11(5):609-28. doi: 10.1586/erv.12.28.
8
The maintaining of the active laboratory-based surveillance of the acute flaccid paralysis (AFP) cases in Romania in the framework of the strategic plan of the global polio eradication initiative.在全球根除脊髓灰质炎行动战略计划框架内，罗马尼亚对急性弛缓性麻痹（AFP）病例开展基于实验室的主动监测。
Roum Arch Microbiol Immunol. 2007 Jan-Jun;66(1-2):44-50.
9
Development and introduction of inactivated poliovirus vaccines derived from Sabin strains in Japan.在日本开发和引进源自 Sabin 株的脊髓灰质炎灭活疫苗。
Vaccine. 2016 Apr 7;34(16):1975-85. doi: 10.1016/j.vaccine.2014.11.015. Epub 2014 Nov 21.
10
Sabin Vaccine Reversion in the Field: a Comprehensive Analysis of Sabin-Like Poliovirus Isolates in Nigeria.现场萨宾疫苗的返祖现象：尼日利亚类似萨宾株脊髓灰质炎病毒分离株的综合分析
J Virol. 2015 Oct 14;90(1):317-31. doi: 10.1128/JVI.01532-15. Print 2016 Jan 1.
引用本文的文献
1
Childhood infectious diseases: experiences and challenges.儿童传染病：经历与挑战。
World J Pediatr. 2025 Jul 10. doi: 10.1007/s12519-025-00941-3.
2
Community-Based Surveillance of Acute Flaccid Paralysis: A Review on Detection and Reporting Strategy.基于社区的急性弛缓性麻痹监测：检测与报告策略综述
J Epidemiol Glob Health. 2025 Feb 20;15(1):29. doi: 10.1007/s44197-025-00349-2.
3
Non-detection of emerging and re-emerging pathogens in wastewater surveillance to confirm absence of transmission risk: A case study of polio in New York.通过废水监测未检测到新出现和再次出现的病原体以确认不存在传播风险：纽约脊髓灰质炎的案例研究
PLOS Glob Public Health. 2024 Dec 31;4(12):e0002381. doi: 10.1371/journal.pgph.0002381. eCollection 2024.
4
Structural and Synthetic Aspects of Small Ring Oxa- and Aza-Heterocyclic Ring Systems as Antiviral Activities.作为抗病毒活性的小环氧杂和氮杂杂环系统的结构和合成方面。
Viruses. 2023 Aug 28;15(9):1826. doi: 10.3390/v15091826.
5
The Uneventful Use of Modern-Day Anesthetic Drugs in Post-polio Paralytic Patients: A Report of Three Cases.现代麻醉药物在小儿麻痹后遗症瘫痪患者中的平稳应用：三例报告
Cureus. 2023 Aug 22;15(8):e43913. doi: 10.7759/cureus.43913. eCollection 2023 Aug.
6
Rebirth of the crippling illness: polio.致残疾病的重生：小儿麻痹症。
Ann Med Surg (Lond). 2023 Mar 27;85(4):1340-1341. doi: 10.1097/MS9.0000000000000286. eCollection 2023 Apr.
7
SAPHO syndrome after COVID-19 vaccination complicated with thyroid function abnormalities: a case report and literature review.新冠病毒疫苗接种后并发甲状腺功能异常的SAPHO综合征：一例报告及文献复习
Immunol Res. 2023 Oct;71(5):781-784. doi: 10.1007/s12026-023-09381-5. Epub 2023 Apr 20.
8
Vaccine-associated enhanced disease in humans and animal models: Lessons and challenges for vaccine development.人类和动物模型中与疫苗相关的增强疾病：疫苗开发的经验与挑战
Front Microbiol. 2022 Aug 10;13:932408. doi: 10.3389/fmicb.2022.932408. eCollection 2022.
9
PAIN IN POST-POLIO SYNDROME: A SEPARATE PAIN ENTITY?小儿麻痹后遗症疼痛：一种独立的疼痛实体？
J Rehabil Med Clin Commun. 2022 Jan 22;5:1000077. doi: 10.2340/20030711-1000077. eCollection 2022.
10
Persistence of poliovirus types 2 and 3 in waste-impacted water and sediment.2型和3型脊髓灰质炎病毒在受垃圾污染的水和沉积物中的持久性。
PLoS One. 2022 Jan 26;17(1):e0262761. doi: 10.1371/journal.pone.0262761. eCollection 2022.
本文引用的文献
1
POLIOMYELITIS VIRUS IN FLY-CONTAMINATED FOOD COLLECTED AT AN EPIDEMIC.在流行地区采集的受苍蝇污染的食物中的脊髓灰质炎病毒。
Science. 1945 May 11;101(2628):491-3. doi: 10.1126/science.101.2628.491.
2
Immune responses in human volunteers upon oral administration of a rodent-adapted strain of poliomyelitis virus.人类志愿者口服适应啮齿动物的脊髓灰质炎病毒株后的免疫反应。
Am J Hyg. 1952 Jan;55(1):108-24. doi: 10.1093/oxfordjournals.aje.a119499.
3
Antibodies to three different antigenic types of poliomyelitis virus in sera from North Alaskan Eskimos.来自阿拉斯加北部爱斯基摩人的血清中针对三种不同抗原类型脊髓灰质炎病毒的抗体。
Am J Hyg. 1951 Sep;54(2):275-85. doi: 10.1093/oxfordjournals.aje.a119485.
4
Problems associated with the use of live poliovirus vaccine.与使用脊髓灰质炎活疫苗相关的问题。
Am J Public Health Nations Health. 1960 Jul;50(7):1013-31. doi: 10.2105/ajph.50.7.1013.
5
Poliomyelitis: its highly invasive nature and narrow stream of infection in a community of high socioeconomic level.
N Engl J Med. 1955 Dec 1;253(22):945-54. doi: 10.1056/NEJM195512012532201.
6
Studies on variants of poliomyelitis virus. I. Experimental segregation and properties of avirulent variants of three immunologic types.脊髓灰质炎病毒变种的研究。I. 三种免疫类型无毒力变种的实验分离及特性
J Exp Med. 1954 Jun 1;99(6):551-76. doi: 10.1084/jem.99.6.551.
7
Environmental virology: from detection of virus in sewage and water by isolation to identification by molecular biology--a trip of over 50 years.环境病毒学：从通过分离检测污水和水中的病毒到通过分子生物学进行鉴定——一段跨越50多年的历程。
Annu Rev Microbiol. 1995;49:461-87. doi: 10.1146/annurev.mi.49.100195.002333.
8
Polioviruses with natural recombinant genomes isolated from vaccine-associated paralytic poliomyelitis.从疫苗相关麻痹型脊髓灰质炎病例中分离出的具有天然重组基因组的脊髓灰质炎病毒。
Virology. 1993 Sep;196(1):199-208. doi: 10.1006/viro.1993.1468.
9
Microevolution of Sabin 1 strain in vitro and genetic stability of oral poliovirus vaccine.萨宾1株的体外微进化及口服脊髓灰质炎病毒疫苗的遗传稳定性
Virology. 1994 Jul;202(1):370-8. doi: 10.1006/viro.1994.1353.
10
Poliomyelitis control in Israel, the West Bank and Gaza Strip: changing strategies with the goal of eradication in an endemic area.以色列、约旦河西岸和加沙地带的脊髓灰质炎控制：在地方流行地区以根除为目标不断变化的策略。
Bull World Health Organ. 1994;72(5):783-96.
Zotero 插件