Samsonov M Iu, Prokaeva T B, Madanat V, Alekberova Z S, Nasonov E L, Fuks D, Vakhter Kh
Klin Med (Mosk). 1995;73(5):53-5.
Neopterin radioimmunoassay measurements (Henning, Berlin) were conducted in 26 male and 12 female patients (mean age 32 +/- 8.01) with Behcet's disease (BD) and healthy controls. In BD patients mean serum neopterin concentrations were significantly higher than in the controls (8.7 +/- 4.1 nmol/l against 5.0 +/- 1.9 nmol/l, respectively). Neopterin levels were higher in patients with positive pathergy test than in negative subjects (p<0.05). There was a significant correlation between neopterin and CRP (rs=0.42. p<0.02). The findings indicate that cellular immunity in BD patients is activated.
对26名男性和12名女性白塞病（BD）患者（平均年龄32±8.01岁）及健康对照者进行了新蝶呤放射免疫分析测定（德国柏林亨宁公司）。BD患者的血清新蝶呤平均浓度显著高于对照组（分别为8.7±4.1 nmol/L和5.0±1.9 nmol/L）。针刺反应试验阳性的患者新蝶呤水平高于阴性患者（p<0.05）。新蝶呤与CRP之间存在显著相关性（rs=0.42，p<0.02）。这些发现表明BD患者的细胞免疫被激活。
