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[前交通动脉瘤破裂后的血管痉挛。经颅多普勒的敏感性和特异性]

[Vasospasm after rupture of aneurysms of the anterior communicating artery. Sensitivity and specificity of transcranial Doppler].

作者信息

Proust F, Hannequin D, Do Marcolino C, Auzou P, Rabehenoina C, Fréger P, Creissard P

机构信息

Service de Neurochirurgie, CHU de Rouen.

出版信息

Neurochirurgie. 1995;41(6):385-90.

PMID:8815412
Abstract

This study was undertaken to determine the sensitivity and specificity of the transcranial Doppler (TCD) for diagnosis of vasospasm after rupture of anterior communicating artery (CoA) aneurysm. Results provided by 164 carotid angiograms and TCD measures were compared in 40 patients with CoA ruptured aneurysm. Twelve patients demonstrated a vasospasm on 22 angiographies. The distribution of angiographic vasospasm was 95.5% anterior cerebral artery (A1), 77.3% pericallosal artery (A2) and 59.1% middle cerebral artery (M1). A TCD velocity value equal or superior to 120 cm/sec was the criterion for TCD vasospasm on M1. The sensitivity of TCD on M1 for diagnosing vasospasm on M1 with high specificity (96.4%) was only 66.7%. A TCD velocity value equal or superior to 80 cm/sec, or superior to the homolateral TCD value on M1, was the criterion for TCD vasospasm on A1. The association of TCD criteria on A1 and M1 increased sensitivity to 83.3%, but specificity decreased to 75%. These results demonstrate that TCD is not yet efficient enough to diagnose vasospasm accurately when it is limited to A1. Moreover, the fact that vasospasm limited to A1-A2 was symptomatic in three patients suggests that angiography is still necessary to diagnose VS after CoA ruptured aneurysm.

摘要

本研究旨在确定经颅多普勒(TCD)诊断前交通动脉(CoA)动脉瘤破裂后血管痉挛的敏感性和特异性。对40例CoA破裂动脉瘤患者的164次颈动脉血管造影结果和TCD测量结果进行了比较。12例患者在22次血管造影中显示有血管痉挛。血管造影显示的血管痉挛分布情况为:大脑前动脉(A1)95.5%,胼周动脉(A2)77.3%,大脑中动脉(M1)59.1%。TCD诊断M1血管痉挛的标准是M1处TCD速度值等于或高于120 cm/秒。TCD诊断M1血管痉挛的敏感性仅为66.7%,但特异性较高(96.4%)。TCD诊断A1血管痉挛的标准是A1处TCD速度值等于或高于80 cm/秒,或高于M1处同侧TCD值。A1和M1处TCD标准联合使用时,敏感性提高到83.3%,但特异性降至75%。这些结果表明,仅局限于A1时,TCD诊断血管痉挛的效率还不够高。此外,3例患者局限于A1 - A2的血管痉挛有症状这一事实表明,CoA破裂动脉瘤后诊断血管痉挛仍需血管造影。

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