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[蝶眶骨脑膜瘤手术治疗的长期结果]

[Long-term results of the surgical treatment of spheno-orbital osteomeningioma].

作者信息

Gaillard S, Lejeune J P, Pellerin P, Pertuzon B, Dhellemmes P, Christiaens J L

机构信息

Clinique Neurochirurgicale, Hôpital B, CHR Lille.

出版信息

Neurochirurgie. 1995;41(6):391-7.

PMID:8815413
Abstract

The authors report a series of 21 cases of spheno-orbital "en plaque" meningiomas operated on between 1981 and 1993. All patients underwent surgery via fronto-temporal approach with orbito-zygomatic removal, followed by bone reconstruction. A complete tumor resection was performed in 15 cases. In the remaining patients, tumor resection remained subtotal, as the cavernous sinus was involved. Histological examination disclosed a low grade meningioma in 17 cases, high grade meningioma in the other patients. Radiation therapy was performed in 5 patients, when the tumoral resection was incomplete or for high grade meningiomas. The mean follow up was 7 years. One patient died in the post-operative course. Transient ophthalmoparesis occurred in 9 cases, 2 patients had pre-operative oculomotor palsy related to tumoral extension in the cavernous sinus and remained unchanged. Visual acuity remained unchanged after surgery in all patients who presented with normal visual acuity. It was unchanged or improved in 63% of patients who presented with moderate visual impairment. Despite the extent of the bone resection, the cosmetic results were good or excellent in 75% of patients, fair in 17%, and bad in 8%. Recurrence of the tumor occurred in 3 patients, with high-grade meningiomas (2 cases) or after subtotal removal of a low-grade meningioma (1 case). Orbito-fronto-temporal approach is necessary to complete the resection of the tumor extended in the orbit, the orbital fissures or the optic canal. Early operation allows a complete tumor resection before the tumor extends to the cavernous sinus.

摘要

作者报告了1981年至1993年间接受手术的21例蝶眶“平板状”脑膜瘤病例。所有患者均通过额颞入路并切除眶颧部,随后进行骨重建。15例患者实现了肿瘤全切。其余患者因海绵窦受累,肿瘤切除仍为次全切除。组织学检查显示17例为低级别脑膜瘤,其他患者为高级别脑膜瘤。5例患者在肿瘤切除不完全或为高级别脑膜瘤时接受了放射治疗。平均随访时间为7年。1例患者在术后病程中死亡。9例患者出现短暂性眼肌麻痹,2例患者术前存在与海绵窦肿瘤扩展相关的动眼神经麻痹且术后未改变。所有视力正常的患者术后视力保持不变。63%有中度视力损害的患者视力不变或改善。尽管骨切除范围较大,但75%的患者美容效果良好或极佳,17%为中等,8%较差。3例患者出现肿瘤复发,其中2例为高级别脑膜瘤,1例为低级别脑膜瘤次全切除术后复发。眶额颞入路对于完全切除延伸至眼眶、眶裂或视神经管的肿瘤是必要的。早期手术可在肿瘤扩展至海绵窦之前实现肿瘤全切。

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