Rossi M, Marin-Neto J, Uchida E, Ramos S
Department of Pathology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Brazil.
Acta Cardiol. 1996;51(3):271-7.
The case reported in this paper, besides illustrating several aspects of the eosinophilic myocarditis, documents a yet undescribed feature of the cardiac involvement in idiopathic hypereosinophilic syndrome characterized by marked basement membrane thickening of small intramyocardial vessels. We are unaware of previous reports showing the presence of an extensive thickening of the basement membrane of arteriolar and capillary intramyocardial vessels in eosinophilic myocarditis. Considering the findings in the present case, i.e., the focal nature of the lesions, the type of necrosis, and the diffuse microangiopathy, it can be hypothesized that the microvascular disease could play a role in the development of the myocardial changes.
本文报道的病例，除了阐明嗜酸性粒细胞性心肌炎的几个方面外，还记录了特发性高嗜酸性粒细胞综合征心脏受累的一个尚未描述的特征，其特点是心肌内小血管基底膜明显增厚。我们不知道之前有报道显示嗜酸性粒细胞性心肌炎中存在心肌内小动脉和毛细血管基底膜广泛增厚的情况。考虑到本病例的发现，即病变的局灶性、坏死类型和弥漫性微血管病，可以推测微血管疾病可能在心肌变化的发展中起作用。
