Roperto F, Brunetti A, Saviano L, Galati P
Vet Pathol. 1996 Jul;33(4):460-2. doi: 10.1177/030098589603300420.
Based upon ultrastructural findings and computed tomography, a presumptive diagnosis of feline primary ciliary dyskinesia was made in a 2.5-year-old cat. The cat demonstrated morphologic alterations in the ultrastructure of oviductal cilia. In the oviduct, axonemal abnormalities were detected in 132 (20%) of 660 cross-sectioned cilia. The main ultrastructural ciliary defects were a lack of central microtubules, transposition of peripheral doublets to the center of the axoneme, supernumerary microtubules, and morphologic abnormalities of peripheral doublets. Computed tomography of the chest was consistent with early lesions of bronchiectasis, suggesting chronic stagnation of respiratory secretions, attributed to abnormal function of respiratory cilia. Specifically, the cranial branches of the cat's bronchi were wider and thicker than those of five healthy controls. Foci of pleural thickening and interstitial enlargement were also observed.
基于超微结构检查结果和计算机断层扫描，对一只2.5岁的猫做出了猫原发性纤毛运动障碍的初步诊断。这只猫的输卵管纤毛超微结构出现了形态学改变。在输卵管中，660根横切纤毛中有132根（20%）检测到轴丝异常。主要的超微结构纤毛缺陷包括中央微管缺失、外周双联体向轴丝中心移位、多余微管以及外周双联体形态异常。胸部计算机断层扫描结果与支气管扩张早期病变相符，提示呼吸道分泌物长期停滞，这归因于呼吸道纤毛功能异常。具体而言，这只猫支气管的头部分支比五只健康对照猫的支气管更宽更厚。还观察到胸膜增厚和间质增宽的病灶。
