促性腺激素释放激素对灌流垂体细胞中雌激素受体信使核糖核酸水平的影响。
Effect of gonadotropin-releasing hormone on estrogen receptor messenger ribonucleic acid level in perifused pituitary cells.
作者信息
Demay F, Tiffoche C, Thieulant M L
机构信息
Laboratorie d' Endocrinologie Moléculaire, URA CNRS 256, Rennes, France.
出版信息
Cell Mol Neurobiol. 1996 Jun;16(3):397-402. doi: 10.1007/BF02088103.
Abstract
- We examined the potential effect of GnRH pulses on pituitary estrogen receptor mRNA level. 2. The treatment of perifused pituitary cell aggregates with four hourly pulses of GnRH (10nM/1 min/h) resulted in a marked increase in the steady-state level of ER mRNA (25% vs unstimulated control, n = 3). 3. No changes were observed for the LH beta mRNA. Data suggest, for the first time, that a cross-talk between the GnRH and nuclear ER may occur in the gonadotrope cells.
摘要
- 我们研究了促性腺激素释放激素（GnRH）脉冲对垂体雌激素受体mRNA水平的潜在影响。2. 用每四小时一次的GnRH脉冲（10nM/1分钟/小时）处理灌流的垂体细胞聚集体，导致雌激素受体mRNA的稳态水平显著增加（与未刺激的对照相比增加25%，n = 3）。3. 促黄体生成素β亚基（LHβ）mRNA未观察到变化。数据首次表明，GnRH与细胞核雌激素受体之间可能在促性腺激素细胞中发生相互作用。
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本文引用的文献
1
Functional cross-talk between receptors for peptide and steroid hormones.肽类激素和甾体激素受体间的功能串扰
Trends Endocrinol Metab. 1992 Dec;3(10):360-5. doi: 10.1016/1043-2760(92)90002-i.
2
Specific, estrogen-sensitive alterations in anterior pituitary cytoplasmic and nuclear estrogen receptors actuated by LHRH.由促黄体生成素释放激素（LHRH）引发的垂体前叶细胞质和细胞核雌激素受体中特定的、雌激素敏感的改变。
Neuroendocrinology. 1983 Aug;37(2):98-105. doi: 10.1159/000123526.
3
Divergent responses of gonadotropin subunit messenger RNAs to continuous versus pulsatile gonadotropin-releasing hormone in vitro.促性腺激素亚基信使核糖核酸在体外对持续与脉冲式促性腺激素释放激素的不同反应。
Mol Endocrinol. 1990 Apr;4(4):557-64. doi: 10.1210/mend-4-4-557.
4
Multiple forms of affinity-labeled estrogen receptors in rat distinct pituitary cells.大鼠不同垂体细胞中多种形式的亲和标记雌激素受体。
Endocrinology. 1992 Sep;131(3):1503-10. doi: 10.1210/endo.131.3.1505480.
5
New insights into activation of the steroid hormone receptor superfamily.类固醇激素受体超家族激活的新见解。
Trends Pharmacol Sci. 1992 Aug;13(8):318-23. doi: 10.1016/0165-6147(92)90099-r.
6
7
Effect of median eminence lesions on [3H]estradiol binding in the anterior pituitary and hypothalamus.正中隆起损伤对垂体前叶和下丘脑中[3H]雌二醇结合的影响。
Endocrinology. 1979 Nov;105(5):1152-7. doi: 10.1210/endo-105-5-1152.
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