Baskin E, Turkay S, Icagasioglu D, Tanzer F, Cevit O
Department of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.
Turk J Pediatr. 1996 Jan-Mar;38(1):119-23.
Guillain-Barre Syndrome (GBS) is the most common cause of acute generalized paralysis. Although the cause and pathogenesis of GBS remain unknown, there is increasing evidence to suggest that this syndrome has an immunological basis. Two children suffering from GBS were treated with high-dose intravenous immune globulin (IVIG) (1 g/kg/day over two consecutive days). Both children showed marked clinical improvement within 48 hours of the onset of treatment. It is suggested, on the basis of recent case reports, that immunoglobulins may have an important role in the treatment of Guillain-Barre Syndrome.
格林-巴利综合征（GBS）是急性全身性麻痹最常见的病因。尽管GBS的病因和发病机制尚不清楚，但越来越多的证据表明该综合征具有免疫学基础。两名患有GBS的儿童接受了大剂量静脉注射免疫球蛋白（IVIG）治疗（连续两天，每天11剂量为1 g/kg）。两名儿童在治疗开始后的48小时内均表现出明显的临床改善。根据最近的病例报告表明，免疫球蛋白可能在格林-巴利综合征的治疗中发挥重要作用。
