Filippov Iu P, Boiarskiĭ M Iu, Brodianskiĭ V M, Ptukha T P
Med Tekh. 1977 Mar-Apr(2):40-4.
When utilizing low temperatures for irreversible destruction of affected biological tissues it is important that one should have a clear idea as to the boundary of necrotic alterations. The correlation between the depth of necrosis and that of freezing, the rate of the tissue congelation, the period of cryogenic action, the temperature of the cryoinstrument and its structural shape, all these factors are analytically interrelated and this enables it to establish optimal performance characteristics in congelation of different tissues. In most cases satisfactory performance characteristics in freezing biological tissues can be achieved by using liquid nitrogen.
当利用低温对受影响的生物组织进行不可逆破坏时，明确坏死性改变的边界非常重要。坏死深度与冷冻深度、组织凝固速率、低温作用时间、冷冻器械的温度及其结构形状之间的相关性，所有这些因素在分析上都是相互关联的，这使得能够确定不同组织冷冻的最佳性能特征。在大多数情况下，使用液氮可以实现令人满意的生物组织冷冻性能特征。
