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[血管内皮的区域结构-代谢特征]

[The regional structural-metabolic characteristics of the vascular endothelium].

作者信息

Gavrish A S, Iashchuk N A

出版信息

Lik Sprava. 1995 Mar-Apr(3-4):118-21.

PMID:8819941
Abstract

The authors studied structural and metabolic features of endothelium of greater vessels (aorta and vena cava posterior) of full-grown rabbits, making use of silver impregnation, transmission electronic microscopy and electronic-histochemical tests for non-compensated negative charges of glycocalyx, oxidoreductase, enzyms determining responsiveness of endotheliocytes in receptor-mediated influences (adenilcyclase and phosphodiesterase). Significant difference was established in respect of the average area of the endothelial stratum elements and total length of intercellular bounderies in the aorta zones with different permeability to Evans blue, as well as of the above measures for the studied arterial and venous portions of the vascular system; some of the regional features of glycocalix and endotheliocyte metabolism were disclosed.

摘要

作者利用银浸染法、透射电子显微镜以及针对糖萼非补偿负电荷、氧化还原酶、决定内皮细胞在受体介导影响下反应性的酶(腺苷酸环化酶和磷酸二酯酶)的电子组织化学测试,研究了成年兔大血管(主动脉和后腔静脉)内皮的结构和代谢特征。在对伊文思蓝具有不同通透性的主动脉区域,内皮细胞层元素的平均面积和细胞间边界的总长度,以及血管系统中研究的动脉和静脉部分的上述指标方面,均发现了显著差异;还揭示了糖萼和内皮细胞代谢的一些区域特征。

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