Hall W, Hando J, Darke S, Ross J
National Drug and Alcohol Research Centre, New South Wales, Australia.
Addiction. 1996 Jan;91(1):81-7. doi: 10.1046/j.1360-0443.1996.9118110.x.
A sample of 301 amphetamine users were interviewed about their experiences of psychological symptoms prior to, and subsequent to, their initiation of amphetamine use. Psychological morbidity was common, with 44% scoring greater than a conservative cut-off of 8 on the General Health Questionnaire. The most commonly reported symptoms subsequent to the onset of amphetamine use were depression (79%), anxiety (76%), paranoia (52%), hallucinations (46%) and violent behaviour (44%). All these symptoms increased in prevalence after the onset of amphetamine use. Route and frequency of amphetamine administration were significant independent predictors of overall psychological morbidity, while route of administration was related to the experience of hallucinations, violent behaviour and paranoia. The avoidance of injection as a route of administration and the use of amphetamines less than weekly are recommended as steps that users can take to reduce the psychological sequelae of amphetamine use.
对301名安非他命使用者进行了访谈，了解他们在开始使用安非他命之前和之后的心理症状经历。心理疾病很常见，44%的人在一般健康问卷上的得分高于保守的临界值8分。使用安非他命后最常报告的症状是抑郁（79%）、焦虑（76%）、偏执（52%）、幻觉（46%）和暴力行为（44%）。所有这些症状在使用安非他命后患病率都有所增加。安非他命的给药途径和频率是总体心理疾病的重要独立预测因素，而给药途径与幻觉、暴力行为和偏执的经历有关。建议避免注射给药途径以及每周使用安非他命少于一次，作为使用者可以采取的减少安非他命使用心理后遗症的措施。
