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[肌电图记录在杜兴氏肌营养不良症携带者检测中的评估]

[Evaluation of electromyographic recordings in the detection of Duchenne's dystrophy carriers].

作者信息

Hausmanowa-Petrusewicz I, Matz B

出版信息

Neurol Neurochir Pol. 1977;11(3):307-13.

PMID:882206
Abstract

The purpose of this work was to compare the possibility of detecting subtle changes in muscular bioelectric activity which are observed in some carriers of Duchenne dystrophy gene using two methods: routine quantitative electromyography and automatic EMG recording (with ANOPS computer). Twenty-one confirmed dystrophy-gene carriers were examined Two muscles were studied in each case: m. biceps brachii and m. quadriceps femoris. There was no difference between the detectability of reduced potential durathion with both methods, but automatic recording made possible a much more accurate determination of the percent of polyphasic potentials. For example, using automatic recording 16.5% of polyphasic potentials were found in the quadriceps femoris muscle of carriers and 15.3% in the biceps brachii muscle, while in routine electromyography these values were respectively 9.9% and 8.9%. This parameter is particularly useful for recognition of very early and slight pathological processes--because of that automatic EMC recording seems to be superior to routine quantitative EMG in the detection of Duchenne dystrophy carriers in whom only very small changes may be expected. In the investigations carried out as yet the authors observed that the introduction of automatic EMG recording raised the detectability rate of gene carriers by 18.9% in relation to the rate of detection by means of CPK determination (previously the EMG raised this rate only by 5 to 9%).

摘要

这项工作的目的是比较使用两种方法检测杜氏肌营养不良症基因携带者中观察到的肌肉生物电活动细微变化的可能性

常规定量肌电图和自动肌电图记录(使用ANOPS计算机)。对21名确诊的肌营养不良症基因携带者进行了检查。每种情况研究两块肌肉:肱二头肌和股四头肌。两种方法在检测电位持续时间缩短方面没有差异,但自动记录使得更准确地确定多相电位的百分比成为可能。例如,使用自动记录,在携带者的股四头肌中发现16.5%的多相电位,在肱二头肌中为15.3%,而在常规肌电图中这些值分别为9.9%和8.9%。由于该参数对于识别非常早期和轻微的病理过程特别有用,因此在检测预期只有非常小变化的杜氏肌营养不良症携带者时,自动肌电图记录似乎优于常规定量肌电图。在迄今为止进行的研究中,作者观察到,与通过肌酸磷酸激酶测定的检测率相比,引入自动肌电图记录使基因携带者的检测率提高了18.9%(以前肌电图仅将该率提高5%至9%)。

相似文献

1
[Evaluation of electromyographic recordings in the detection of Duchenne's dystrophy carriers].[肌电图记录在杜兴氏肌营养不良症携带者检测中的评估]
Neurol Neurochir Pol. 1977;11(3):307-13.
2
[Prevention of duchenne's muscular dystrophy: methodological problems in the detection of carriers (author's transl)].
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Quantitative electromyography in the detection of the carriers in Duchenne type muscular dystrophy.定量肌电图在杜氏型肌营养不良症携带者检测中的应用
J Neurol. 1976 Apr 23;212(2):139-49. doi: 10.1007/BF00329157.
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