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Compositional analysis surveillance of eleven brands of enrofloxacin including Baytril for veterinary use.

作者信息

Sumano H, Ocampo L

机构信息

Department of Physiology and Pharmacology, Veterinary College, National Autonomous University of Mexico, Mexico City.

出版信息

Zentralbl Veterinarmed A. 1995 Dec;42(10):669-73. doi: 10.1111/j.1439-0442.1995.tb00421.x.

DOI:10.1111/j.1439-0442.1995.tb00421.x
PMID:8822191
Abstract

Lack of consistency in clinical effectiveness of various commercial preparations of enrofloxacin prompted a compositional analysis surveillance of 11 trade marks of this fluoroquinolone using various physicochemical properties and high performance liquid chromatography (HPLC). Only one preparation resembled Baytril (Bayer of Mexico), the original brand of enrofloxacin. Variations in the concentration of enrofloxacin, use of different vehicles, substitution of this fluoroquinolone by ciprofloxacin and variations in pH were found. The use of ciprofloxacin in veterinary medicine is discussed.

摘要

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