Kuspis D A, Krenzelok E P
Pittsburgh Poison Center, Children's Hospital of Pittsburgh, PA 15213, USA.
Vet Hum Toxicol. 1996 Feb;38(1):48-9.
Improperly disposed-of expired medications pose a significant risk to children. To determine how expired medications are disposed of, 500 callers to our poison information center, 100 community and hospital pharmacies, the state Boards of Pharmacy, and the FDA and EPA were surveyed about medication disposal habits. Of the 500 people polled, 1.4% returned medications to a pharmacy, 54% disposed of medications in the garbage, 35.4% flushed medications down the toilet or sink, 7.2% did not dispose of medications, and 2% related they used all medications before expiration. Of the 100 pharmacies surveyed, all but 3% had specific policies on the disposal of undispensed expired medications, which were usually returned to the producer. Alternative disposal means used for nonreturnable medications were incineration (15%), hazardous waste disposal contracts (17%), and conventional solid waste disposal or down the toilet (68%). Only 5% of the 100 pharmacies had consistent recommendations for their customers on drug disposal; 25% of the pharmacies indicated questions on drug disposal were handled by individual pharmacists only upon consumer request. A variety of drug disposal techniques were encountered in our survey. Pharmacies had specific policies for expired undispensed pharmaceuticals, but lacked uniform guidelines. Little information on the safe disposal of medications was routinely passed on to the public. Uniform guidelines need to be created for the safe disposal of expired medications and should be included in routine consumer education provided by poison information centers and pharmacies.
不当处置过期药品会对儿童构成重大风险。为了确定过期药品是如何被处置的,我们对拨打毒物信息中心电话的500人、100家社区和医院药房、州药房委员会以及美国食品药品监督管理局(FDA)和美国环境保护局(EPA)进行了关于药品处置习惯的调查。在接受调查的500人中,1.4%将药品返还给药房,54%将药品丢弃在垃圾中,35.4%将药品冲进马桶或水槽,7.2%未处置药品,2%表示他们在药品过期前用完了所有药品。在接受调查的100家药房中,除3%外,其他药房都有关于未分发过期药品处置的具体政策,这些药品通常返还给生产商。对于不可返还的药品,采用的其他处置方式包括焚烧(15%)、危险废物处置合同(17%)以及常规固体废物处置或冲进马桶(68%)。在100家药房中,只有5%向顾客提供了关于药品处置的一致建议;25%的药房表示,只有在消费者提出要求时,个别药剂师才会处理有关药品处置的问题。我们的调查中遇到了多种药品处置技术。药房对过期未分发的药品有具体政策,但缺乏统一的指导方针。关于药品安全处置的信息很少定期传达给公众。需要制定统一的指导方针,以安全处置过期药品,并且应将其纳入毒物信息中心和药房提供的常规消费者教育中。