Parnaik V K
Centre for Cellular and Molecular Biology, Hyderabad, India.
Indian J Biochem Biophys. 1996 Jun;33(3):164-7.
Nucleocytoplasmic transport of proteins occurs through pores embedded in the nuclear envelope. Recent studies have defined the cytoplasmic factors required for signal-mediated import of nuclear proteins. Considerable progress has been made in understanding the mechanism of nuclear export of proteins by the identification of specific signal sequences needed for export. Regulatory molecules have been shown to adopt novel mechanisms to control their entry into the nucleus and thereby regulate their functions.
蛋白质的核质运输通过嵌入核膜的孔道进行。最近的研究已经明确了信号介导的核蛋白输入所需的细胞质因子。通过鉴定输出所需的特定信号序列，在理解蛋白质核输出机制方面取得了相当大的进展。已表明调节分子采用新机制来控制其进入细胞核，从而调节其功能。
