Shirasawa B, Hamano K, Ito H, Gohra H, Katoh T, Fujimura Y, Tsuboi H, Esato K
First Department of Surgery, Yamaguchi University School of Medicine, Ube, Japan.
Kyobu Geka. 1996 Sep;49(10):809-12.
Recently, coronary artery bypass grafting (CABG) has been performed safely in patients maintained on hemodialysis. However, the postoperative immunological capacity of patients undergoing CABG during chronic hemodialysis has not been fully investigated. Recently we performed CABG in a patient undergoing chronic hemodialysis and measured the immunological parameters. The WBC count, the populations of lymphocytes, OKT 4-positive cells, and OKT 8-positive cells, and NK activity were determined, and the lymphocyte stimulation test (using PHA) was performed before and after cardiopulmonary bypass, then, 1, 3, and 6 days after CABG. We compared these data with those from 17 patients without chronic hemodialysis. The immunological capacity after CABG in the patient with chronic hemodialysis was similar to that of patients without chronic hemodialysis. We suggest that CABG in patients with chronic hemodialysis is a safe operation with regard to the immunological capacity.
最近，冠状动脉旁路移植术（CABG）已在接受血液透析的患者中安全实施。然而，慢性血液透析期间接受CABG患者的术后免疫能力尚未得到充分研究。最近，我们对一名接受慢性血液透析的患者实施了CABG，并测量了免疫参数。测定了白细胞计数、淋巴细胞群体、OKT 4阳性细胞、OKT 8阳性细胞以及自然杀伤细胞（NK）活性，并在体外循环前后、CABG术后1天、3天和6天进行了淋巴细胞刺激试验（使用PHA）。我们将这些数据与17名无慢性血液透析患者的数据进行了比较。慢性血液透析患者CABG术后的免疫能力与无慢性血液透析患者相似。我们认为，就免疫能力而言，慢性血液透析患者进行CABG是一种安全的手术。
