Yano M, Yamakawa Y, Niwa H, Fukai I, Kiriyama M, Saito Y, Kani H, Sasaki H, Masaoka A
Second Department of Surgery, Nagoya City University School of Medicine, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1996 Aug;44(8):1114-8.
Sixteen cases with mediastinal malignant lymphoma were treated in our department and a correlation made between the prognosis and other factors: first symptom, maximum diameter of the tumor, type of operation, pathological subtype, clinical stage. First symptom and compressed or invasive symptom with mediastinal mass were not related to prognosis. The cases with bulky tumor over 10 cm in diameter showed a tendency toward poorer prognosis. Complete or incomplete resection did not have significant effect. The cases of Hodgkin's disease had relatively good prognosis. Classification of clinical stage (Ann Arbor classification) did not show significant correlation with prognosis and may be inadequate for staging of mediastinal malignant lymphoma. Surgical treatment may be adapted for mediastinal Hodgkin's disease and early stages of thymic malignant lymphoma.
我科共收治16例纵隔恶性淋巴瘤患者，并对预后与其他因素进行了相关性分析：首发症状、肿瘤最大直径、手术方式、病理亚型、临床分期。首发症状及纵隔肿块的压迫或浸润症状与预后无关。肿瘤直径超过10cm的巨大肿块患者预后有较差的倾向。完整或不完整切除对预后无显著影响。霍奇金病患者预后相对较好。临床分期（Ann Arbor分期）与预后无显著相关性，可能不足以对纵隔恶性淋巴瘤进行分期。手术治疗适用于纵隔霍奇金病及胸腺恶性淋巴瘤早期。
