Fanning J, Markuly S N, Hindman T L, Galle P C, McRae M A, Visnesky P M, Hilgers R D
Department of Obstetrics and Gynecology, Southern Illinois University School of Medicine, Carbondale, USA.
J Reprod Med. 1996 Jul;41(7):504-8.
To determine the incidence of false positive malignant peritoneal cytology and psammoma bodies associated with benign gynecologic disorders.
Pelvic peritoneal fluid was prospectively collected for cytologic examination from 119 women undergoing laparoscopy for benign conditions (infertility, 67; pelvic pain, 35; elective sterilization, 17). The median age was 30. No patient had laparoscopic gross cancer or histologic evidence of cancer.
The peritoneal cytology of 2 of 119 cases (2%) contained cells with features suggestive of malignancy, and 6 of 119 cases (5%) contained psammoma bodies. Both cases of false positive peritoneal cytology and four of six with psammoma bodies were associated with endometriosis. All cases were followed for a minimum of two years, and no patient had developed cancer.
Peritoneal fluid from cases of benign gynecologic disorders, especially endometriosis, can contain psammoma bodies and cells suggestive of malignancy.
确定与良性妇科疾病相关的恶性腹膜细胞学假阳性和砂粒体的发生率。
前瞻性收集119例因良性疾病（不孕症67例、盆腔疼痛35例、择期绝育17例）接受腹腔镜检查的女性的盆腔腹膜液进行细胞学检查。中位年龄为30岁。无患者有腹腔镜下肉眼可见的癌症或癌症组织学证据。
119例中有2例（2%）的腹膜细胞学检查发现具有恶性特征的细胞，119例中有6例（5%）含有砂粒体。腹膜细胞学假阳性的2例以及含砂粒体的6例中的4例均与子宫内膜异位症有关。所有病例均随访至少两年，无患者发生癌症。
良性妇科疾病患者的腹膜液，尤其是子宫内膜异位症患者，可含有砂粒体和提示恶性的细胞。
