Sage A E, Proctor W D, Phibbs P V
Department of Microbiology and Immunology, East Carolina University School of Medicine, Greenville, North Carolina 27858-4354, USA.
J Bacteriol. 1996 Oct;178(20):6064-6. doi: 10.1128/jb.178.20.6064-6066.1996.
A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa.
在铜绿假单胞菌PAO1中鉴定出一个729个碱基对的开放阅读框(gltR),其编码一种与双组分应答调节蛋白家族同源的产物。gltR的破坏导致葡萄糖转运活性丧失。gltR的恢复导致葡萄糖转运达到野生型水平。这些发现表明,gltR是铜绿假单胞菌中葡萄糖转运系统表达所必需的。