Ishii M, Jones M, Shiota T, Heinrich R, Yamada I, Sinclair B, Yoganathan A P, Sahn D J
Oregon Health Sciences University, Portland, USA.
Am Heart J. 1996 Oct;132(4):796-804. doi: 10.1016/s0002-8703(96)90314-2.
To evaluate the utility of measurements of the color Doppler jet area, jet length, and width of the color Doppler-imaged vena contracta (the smallest flow diameter in any part of the flow acceleration field) as methods for quantifying aortic regurgitation (AR), eight sheep with surgically induced AR were studied. AR was quantified as peak and mean regurgitant flow rates, regurgitant stroke volumes, and regurgitant fractions as determined with pulmonary and aortic electromagnetic flow probes and flowmeters balanced against each other. Simple linear regression analysis between the maximal color jet areas, jet length, and flowmeter data showed only moderately good correlation (jet area: 0.42 < or = r < or = 0.57, SEE = 2.85 cm2; jet length: 0.42 < or = r < or = 0.59, SEE = 1.23 cm). In contrast, the width of color Doppler-imaged vena contracta was a better indicator of the severity of AR on the basis of the electromagnetic flowmeter methods (0.73 < or = r < or = 0.90, SEE = 0.15 cm). Therefore the color Doppler jet length and jet area methods have limited use for determining AR, whereas the width of the color Doppler-imaged vena contracta can be used for quantifying the severity of AR.
为评估彩色多普勒血流束面积、血流束长度及彩色多普勒成像的瓣口反流束宽度（血流加速场中任何部位的最小血流直径）作为量化主动脉瓣反流（AR）方法的实用性，对8只通过手术造成AR的绵羊进行了研究。AR通过肺和主动脉电磁血流探头及相互校准的流量计测定的反流峰值流速、平均反流流速、反流搏出量和反流分数进行量化。最大彩色血流束面积、血流束长度与流量计数据之间的简单线性回归分析显示相关性仅为中等程度（血流束面积：0.42≤r≤0.57，标准估计误差[SEE]=2.85cm²；血流束长度：0.42≤r≤0.59，SEE=1.23cm）。相比之下，基于电磁流量计方法，彩色多普勒成像的瓣口反流束宽度是AR严重程度更好的指标（0.73≤r≤0.90，SEE=0.15cm）。因此，彩色多普勒血流束长度和血流束面积方法在确定AR方面用途有限，而彩色多普勒成像的瓣口反流束宽度可用于量化AR的严重程度。
