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惠普尔病患者肝脏中的杆状生物体。

Rod-shaped organism in the liver of a patient with Whipple's disease.

作者信息

Viteri A L, Stinson J C, Barnes M C, Dyck W P

出版信息

Dig Dis Sci. 1979 Jul;24(7):560-4. doi: 10.1007/BF01489326.

DOI:10.1007/BF01489326
PMID:88317
Abstract

Histological review of a liver biopsy from a patient with known Whipple's disease revealed a prominence of Kupffer cells containing PAS-positive granules. Electron microscopy revealed rod-shaped organisms in the Kupffer cells but the presence of these structures were not associated with overt liver injury. This is thought to be the first reported demonstration of these bacillary bodies in this location.

摘要

对一名已知患有惠普尔病患者的肝脏活检组织进行组织学检查发现,库普弗细胞显著增多,且含有PAS阳性颗粒。电子显微镜检查显示库普弗细胞内存在杆状生物体,但这些结构的存在与明显的肝损伤无关。据认为,这是首次报道在该部位发现这些杆菌体。

相似文献

1
Rod-shaped organism in the liver of a patient with Whipple's disease.惠普尔病患者肝脏中的杆状生物体。
Dig Dis Sci. 1979 Jul;24(7):560-4. doi: 10.1007/BF01489326.
2
Pancarditis in Whipple's disease: electronmicroscopic demonstration of intracardiac bacillary bodies.
Am J Clin Pathol. 1976 Jul;66(1):22-30. doi: 10.1093/ajcp/66.1.22.
3
Bacilli-lipid associations in Whipple's disease.惠普尔病中的杆菌-脂质关联
J Pathol Bacteriol. 1967 Jul;94(1):131-7. doi: 10.1002/path.1700940117.
4
Detection by electron microscope of rod-shaped organisms in synovial membrane from a patient with the arthritis of Whipple's disease.在惠普尔病关节炎患者的滑膜中通过电子显微镜检测到杆状生物体。
Ann Rheum Dis. 1976 Dec;35(6):502-9. doi: 10.1136/ard.35.6.502.
5
Whipple's disease: a review emphasizing immunology and microbiology.惠普尔病:一篇着重于免疫学和微生物学的综述
Crit Rev Clin Lab Sci. 1981;14(2):75-108. doi: 10.3109/10408368109106451.
6
Sarcoidlike granulomas as an early manifestation of Whipple's disease.类肉瘤样肉芽肿作为惠普尔病的早期表现
Gastroenterology. 1984 Oct;87(4):941-7.
7
An electron-microscope study of bacteria in two cases of Whipple's disease.两例惠普尔病细菌的电子显微镜研究
J Pathol. 1970 Apr;100(4):249-55. doi: 10.1002/path.1711000404.
8
[An electronmicroscopic contribution to Whipple's disease].[电子显微镜对惠普尔病的研究贡献]
Beitr Pathol Anat. 1969;139(1):12-36.
9
Hepatic and appendiceal Whipple's disease with negative jejunal biopsies.
Am J Gastroenterol. 1981 Apr;75(4):302-6.
10
[Endoscopic findings in Whipple's disease (author's transl)].
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本文引用的文献

1
WHIPPLE'S DISEASE: LIGHT AND ELECTRON MICROSCOPE CORRELATION OF JEJUNAL MUCOSAL HISTOLOGY WITH ANTIBIOTIC TREATMENT AND CLINICAL STATUS.惠普尔病:空肠黏膜组织学的光镜与电镜观察结果与抗生素治疗及临床状态的相关性
Gastroenterology. 1965 Jun;48:684-707.
2
Combined electron and light microscopy in Whipple's disease. Demonstration of "bacillary bodies" in the intestine.惠普尔病的电子显微镜与光学显微镜联合检查。肠道内“杆菌小体”的显示。
Bull Johns Hopkins Hosp. 1961 Aug;109:80-98.
3
Electron microscopic study of the intestinal mucosa in Whipple's disease. Demonstration of encapsulated bacilliform bodies in the lesion.
惠普尔病肠道黏膜的电子显微镜研究。病变中包囊状杆菌样小体的显示。
Gastroenterology. 1961 Aug;41:129-38.
4
Whipple's disease; observations on systemic involvement. II. Gross and histologic observations.惠普尔病;全身受累情况观察。II.大体及组织学观察
AMA Arch Pathol. 1959 Jan;67(1):81-93.
5
Whipple's disease: a review of 19 patients from one hospital and a review of the literature since 1950.
Medicine (Baltimore). 1970 May;49(3):175-205.
6
Granulomatous encephalitis in Whipple's disease. Electron miscroscopic observations.
Acta Neuropathol. 1969;13(1):1-11. doi: 10.1007/BF00686137.
7
A light- and electron-microscopic study of bacterial invasion in Whipple's disease.惠普尔病中细菌侵袭的光镜和电镜研究。
Am J Pathol. 1967 Aug;51(2):225-42.
8
Detection by electron microscope of rod-shaped organisms in synovial membrane from a patient with the arthritis of Whipple's disease.在惠普尔病关节炎患者的滑膜中通过电子显微镜检测到杆状生物体。
Ann Rheum Dis. 1976 Dec;35(6):502-9. doi: 10.1136/ard.35.6.502.
9
Pancarditis in Whipple's disease: electronmicroscopic demonstration of intracardiac bacillary bodies.
Am J Clin Pathol. 1976 Jul;66(1):22-30. doi: 10.1093/ajcp/66.1.22.
10
Whipple's disease. An example of the value of the electron microscope in diagnosis, follow-up, and correlation of a pathologic process.惠普尔病。电子显微镜在诊断、随访及病理过程关联方面价值的一个实例。
Hum Pathol. 1975 Jul;6(4):443-54. doi: 10.1016/s0046-8177(75)80062-1.