Briceno I, Bernal J E, Duran C, Ortega J, Umana A, Gomez A, Papiha S S
Instituto de Genetica Humana, Universidad Javeriana, Bogota, Columbia.
Eur J Immunogenet. 1996 Feb;23(1):21-8. doi: 10.1111/j.1744-313x.1996.tb00261.x.
Serological HLA types (A, B, C, DR and DQ loci) were studied in five different Indian tribes (Cubeo, Tucano, Coreguaje, Embera and Noanama) belonging to two distinct linguistic families. For all the MHC loci, the range of variation among the five tribes was enormous. Two tribes, Cubeo and Tucano, showed a wide spectrum of antigenic specificities which seemed to be due to admixture from non-tribal groups, while in the other three tribes the polymorphisms of various HLA loci showed restricted distributions. The gene frequency data, when converted to a kinship matrix and a two-dimensional eigenvector plot, indicated that members of the same linguistic family tend to have greater genetic affinity.
对属于两个不同语系的五个不同印度部落（库贝奥人、图卡诺人、科雷瓜耶人、恩贝拉人和诺亚纳马人）的血清学HLA类型（A、B、C、DR和DQ位点）进行了研究。对于所有主要组织相容性复合体（MHC）位点，这五个部落之间的变异范围极大。库贝奥和图卡诺这两个部落表现出广泛的抗原特异性谱，这似乎是由于非部落群体的混合，而在其他三个部落中，各种HLA位点的多态性显示出有限的分布。当将基因频率数据转换为亲缘关系矩阵和二维特征向量图时，表明同一语系的成员往往具有更高的遗传亲和力。
