Nicolle L E, Bentley D, Garibaldi R, Neuhaus E, Smith P
Long-Term-Care Committee, Society for Healthcare Epidemiology of America, Woodbury, NJ 08096-3172, USA.
Infect Control Hosp Epidemiol. 1996 Feb;17(2):119-28. doi: 10.1086/647256.
There is intense antimicrobial use in long-term-care facilities (LTCF), and studies repeatedly document that much of this use is inappropriate. The current crisis in antimicrobial resistance, which encompasses the LTCF, heightens concerns of antimicrobial use. Attempts to improve antimicrobial use in the LTCF are complicated by characteristics of the patient population, limited availability of diagnostic tests, and virtual absence of relevant clinical trials. This article recommends approaches to management of common LTCF infections and proposes minimal standards for an antimicrobial review program. In developing these recommendations, the article acknowledges the unique aspects of provision of care in the LTCF.
长期护理机构（LTCF）中抗菌药物的使用十分频繁，多项研究反复表明，其中大部分使用是不合理的。当前包括长期护理机构在内的抗菌药物耐药性危机加剧了人们对抗菌药物使用的担忧。由于患者群体的特点、诊断检测的可及性有限以及几乎没有相关临床试验，改善长期护理机构抗菌药物使用的尝试变得复杂。本文推荐了常见长期护理机构感染的管理方法，并提出了抗菌药物审查项目的最低标准。在制定这些建议时，本文承认了长期护理机构护理服务的独特之处。
