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初级听觉和网状结构中的频率跟随反应。

Frequency-following responses in primary auditory and reticular formation structures.

作者信息

Faingold C L, Caspary D M

出版信息

Electroencephalogr Clin Neurophysiol. 1979 Jul;47(1):12-20. doi: 10.1016/0013-4694(79)90028-2.

DOI:10.1016/0013-4694(79)90028-2
PMID:88357
Abstract

The responses of the cat brain to tonal stimuli were recorded from the inferior colliculus, medial geniculate, reticular formation and the far field. The response consisted of an onset component and a frequency-following response (FFR) component in the inferior colliculus (IC) and the far field. In contrast to previous work, the FFR was also observed in the reticular formation. The response in the reticular formation was abolished at lower doses of pentobarbital and at lower relative intensities of masking than that in the IC and far field. The amplitude of the FFR increased and the latency decreased with progressive ventral movement of the electrode through the IC. The onset component of the response in IC was more easily masked than the FFR component, while the FFR component was depressed to a somewhat greater extent by pentobarbital administration. These findings suggest that the different components of the response to tonal stimuli are generated by different mechanisms.

摘要

从猫的下丘、内侧膝状体、网状结构和远场记录了猫脑对音调刺激的反应。在下丘(IC)和远场,反应由起始成分和频率跟随反应(FFR)成分组成。与之前的研究不同,在网状结构中也观察到了FFR。与IC和远场相比,较低剂量的戊巴比妥和较低相对强度的掩蔽就能消除网状结构中的反应。随着电极在IC中逐渐向腹侧移动,FFR的幅度增加,潜伏期缩短。IC中反应的起始成分比FFR成分更容易被掩蔽,而FFR成分在注射戊巴比妥后受到的抑制程度更大。这些发现表明,对音调刺激反应的不同成分是由不同机制产生的。

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