Hanneman G D, Higgins E A, Price G T, Funkhouser G E, Grape P M, Snyder L
Am J Vet Res. 1977 Jul;38(7):955-8.
Heat-induced hyperthermia can be a major problem in dogs shipped during summer months. Dogs shipped by air transport can encounter temperatures as high as 54.4 C. Usually, little concern is given to effects produced by hyperthermia. To assess the heat stress problem, 20 dogs were exposed to a temperature of 54.4 C for 30 minutes--10 dogs at 15% relative humidity and 10 dogs at 35%. Dogs did not die as a result of exposure, but certain transient and permanent changes occurred. All dogs had increased heart rate, rectal temperature, blood pH, hemoglobin concentration, packed cell volume, and erythrocyte count. Body weight and PVCO2, decreased. Differences also were shown between the 2 humidity group for blood PH PVCO2, rectal temperature, and weight loss. The major tissue changes attributed to hyperthermia were fragmentation of the myocardium, acute cortical necrosis in kidney, and marked degenerative changes in the cerebellum and cerebral cortex. Changes in the cerebellum and cerebral cortex were considered severe and permanent.
在夏季运输的犬只中，热诱导的体温过高可能是一个主要问题。通过航空运输的犬只可能会遇到高达54.4摄氏度的温度。通常，人们很少关注体温过高所产生的影响。为了评估热应激问题，将20只犬暴露在54.4摄氏度的温度下30分钟——10只犬处于15%的相对湿度，10只犬处于35%的相对湿度。犬只并未因暴露而死亡，但出现了某些短暂和永久性的变化。所有犬只的心率、直肠温度、血液pH值、血红蛋白浓度、红细胞压积和红细胞计数均升高。体重和静脉二氧化碳分压降低。两个湿度组在血液pH值、静脉二氧化碳分压、直肠温度和体重减轻方面也存在差异。归因于体温过高的主要组织变化是心肌碎裂、肾脏急性皮质坏死以及小脑和大脑皮质的明显退行性变化。小脑和大脑皮质的变化被认为是严重且永久性的。
