Süer S, Ulutin T, Sönmez H, Kökoğlu E, Uçişik N, Bayram C, Sultuybek G
Department of Biochemistry, Istanbul University, Cerrahpaşa Medical Faculty, Turkey.
Thromb Res. 1996 Jul 1;83(1):77-85. doi: 10.1016/0049-3848(96)00105-3.
In this study we investigated serum Lp(a) and plasma t-PA-PAI-1 complex levels in patients with coronary heart disease (CHD). Serum total cholesterol, triglyceride, LDL and VDL cholesterol levels (p < 0.001) and HDL cholesterol levels (p < 0.01) in patients group were found to be significantly different from those in control group. The mean Lp(a) and t-PA-PAI-1 complex levels in patients with coronary heart disease were significantly higher as compared to control group (p < 0.001). This data indicate that the elevated levels of serum Lp(a) and plasma t-PA-PAI-1 complex may play an important role in the pathogenesis of coronary atherosclerosis.
