Ordóñez N G, Myhre M, Mackay B
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
Ultrastruct Pathol. 1996 Jul-Aug;20(4):331-6. doi: 10.3109/01913129609016333.
A clear cell form of epithelial mesothelioma is described. This variant does not appear to have been previously described, and it merits recognition since it is readily confused by routine light microscopy with other tumors that involve the pleura, including metastatic carcinomas composed predominantly of cells with optically clear cytoplasm. Ultrastructural and immunohistochemical studies were helpful in reaching the diagnosis in this case, and electron microscopy is particularly recommended to investigate the differential diagnosis of unusual pleural tumors.
描述了一种上皮性间皮瘤的透明细胞形态。这种变体似乎以前未曾被描述过,它值得被识别,因为在常规光学显微镜下它很容易与其他累及胸膜的肿瘤混淆,包括主要由具有光学透明细胞质的细胞组成的转移性癌。超微结构和免疫组织化学研究有助于该病例的诊断,特别推荐使用电子显微镜来研究不寻常胸膜肿瘤的鉴别诊断。