Chow W H, Ji B T, Dosemeci M, McLaughlin J K, Gao Y T, Fraumeni J F
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA.
Am J Ind Med. 1996 Jul;30(1):36-40. doi: 10.1002/(SICI)1097-0274(199607)30:1<36::AID-AJIM6>3.0.CO;2-Q.
Using occupational data for more than 500 patients with cancers of the biliary tract (CBT) diagnosed between 1980 and 1984 in Shanghai, and employment information from the 1982 census for the Shanghai population, the associations between CBT and occupational categories were examined by standardized incidence ratios (SIR). Compared to the general population, risk was elevated by nearly 40% among textile workers (SIR for women = 137, 95% CI = 106-175 and SIR for men = 137, 95% CI = 76-217), consistent with other investigations linking CBT to textile work. Increased risks were observed also among waiters/ waitresses, male sanitation personnel and chemical workers, and female janitor and similar workers. Although causal inferences cannot be firmly drawn, our findings add to the limited evidence linking CBT to occupational exposures, especially in the textile industry.
利用1980年至1984年期间在上海诊断出的500多名胆管癌(CBT)患者的职业数据,以及1982年上海人口普查的就业信息,通过标准化发病率(SIR)研究了CBT与职业类别的关联。与普通人群相比,纺织工人的风险升高了近40%(女性SIR = 137,95% CI = 106 - 175;男性SIR = 137,95% CI = 76 - 217),这与其他将CBT与纺织工作联系起来的调查结果一致。在男女服务员、男性卫生人员和化学工人以及女性门卫和类似工人中也观察到风险增加。尽管不能确凿地得出因果推断,但我们的研究结果增加了将CBT与职业暴露联系起来的有限证据,特别是在纺织行业。