Allen C B
Department of Nutrition, University of California, Davis 95616-8669, USA.
Physiol Behav. 1996 Feb;59(2):247-53. doi: 10.1016/0031-9384(95)02033-0.
Weanling male rats were fed either copper-adequate (CuA) or copper-deficient (CuD) diets ad lib for 20 wk. A pair-fed group was also studied. Two relative food intake indices (RFIs) and a growth efficiency (GE) index were calculated. Body weights of the CuD group became reduced compared to the CuA group starting the sixth week of the study. Copper deficiency was found to affect both of the RFI indices and the GE index in a time-dependent manner. RFIs and GE were reduced early, but recovered towards the control values during the last half of the experimental period. At the end of 20 wk, organ copper content and serum ceruloplasmin was reduced in the CuD group. Dietary copper deficiency reduces growth rate through effects both on food intake and efficiency of food utilization for growth.
将断乳雄性大鼠随意喂食充足铜（CuA）或缺铜（CuD）饲料，持续20周。同时研究了一对喂食组。计算了两个相对食物摄入量指数（RFI）和一个生长效率（GE）指数。从研究的第六周开始，与CuA组相比，CuD组的体重下降。发现缺铜以时间依赖的方式影响RFI指数和GE指数。RFI和GE在早期降低，但在实验期的后半段恢复到对照值。在20周结束时，CuD组的器官铜含量和血清铜蓝蛋白降低。膳食铜缺乏通过对食物摄入量和生长所需食物利用效率的影响来降低生长速率。
