Frick G, Preussner S, Perlberg K W
Folia Haematol Int Mag Klin Morphol Blutforsch. 1979;106(1):53-64.
The pathogenetic bases for the indication of immunosuppression in multiple sclerosis are represented in a survey, rested upon experiences in the clinical compatability test of AHLG Dessau. The knowledge gained in animal experiments and epidemiology in recent years is considered and problems of membrane, slow-virus hypothesis, genetic problems and changes of immunoglobulins and lymphocytes are critically referred to.
基于德绍AHLG临床适应性试验的经验,一项调查阐述了多发性硬化症中免疫抑制指征的发病基础。文中考虑了近年来在动物实验和流行病学中获得的知识,并批判性地提及了膜问题、慢病毒假说、遗传问题以及免疫球蛋白和淋巴细胞的变化。