Sadi A M, Toda T, Kiyuna M, Tamamoto T, Kina K, Hirayasu K, Yara A
Department of Clinical Laboratory Medicine, University of the Ryukyus, Okinawa, Japan.
Acta Paediatr Jpn. 1996 Aug;38(4):361-4. doi: 10.1111/j.1442-200x.1996.tb03507.x.
A primigravida delivered a cyanosed female infant with a very low Apgar score. Cardiac anomaly of the fetus was detected at 32 weeks of gestation by ultrasonography. The baby died on the day of delivery. Autopsy revealed multiple tumor masses in the interventricular septum and ventricular walls. The tumor originating from the interventricular septum was the largest and measured 3.7 x 3 cm. Histologically, the tumor was composed of large polygonal glycogen-laden cells and 'spider-cells'. Eosinophilic giant histiocytic cells were also observed in the spleen. Ultrastructural features of the tumor cells correlated with those of typical cardiac muscle cells.
一名初产妇分娩出一名面色青紫的女婴，阿氏评分极低。妊娠32周时通过超声检查发现胎儿心脏异常。婴儿在分娩当天死亡。尸检显示室间隔和心室壁有多个肿瘤肿块。起源于室间隔的肿瘤最大，尺寸为3.7×3厘米。组织学上，肿瘤由充满糖原的大的多边形细胞和“蜘蛛细胞”组成。在脾脏中也观察到嗜酸性巨型组织细胞。肿瘤细胞的超微结构特征与典型心肌细胞的特征相关。
