Düzgüneş N, Ohki S
Biochim Biophys Acta. 1977 Jun 16;467(3):301-8. doi: 10.1016/0005-2736(77)90307-8.
The interaction of unilamellar phospholipid vesicles with bilayer lipid membranes has been studied by observing the electrical conductance of the planar membrane. The presence of phosphatidylcholine vesicles as well as phosphatidylcholine/phosphatidylserine (1 : 1) vesicles on one side compartment of the bilayer membrane, but not phosphatidylserine vesicles, causes discrete fluctuations in the phosphatidylserine membrane conductance, which is also increased by at least an order of magnitude. These events are dependent on vesicle concentration as well as the presence of Ca2+. The results are interpreted in terms of the incorporation of domains of phosphatidylcholine into the membrane, which confer a higher conductance state.
通过观察平面膜的电导，研究了单层磷脂囊泡与双层脂质膜的相互作用。双层膜一侧隔室中存在磷脂酰胆碱囊泡以及磷脂酰胆碱/磷脂酰丝氨酸（1:1）囊泡，但不存在磷脂酰丝氨酸囊泡时，会导致磷脂酰丝氨酸膜电导出现离散波动，且电导至少增加一个数量级。这些事件取决于囊泡浓度以及Ca2+的存在。结果表明，磷脂酰胆碱结构域掺入膜中，赋予了更高的电导状态。
