Haqqie S S, Urizar R E, Singh J
Stratton Veterans Affairs Medical Center, Albany, NY 12208, USA.
Am J Kidney Dis. 1996 Oct;28(4):493-501. doi: 10.1016/s0272-6386(96)90458-8.
The protean clinical manifestations of atheroembolic disease (AED) mimic systemic disorders with kidney involvement. Acute or chronic renal failure develops spontaneously or more frequently after an inciting event in patients with AED. Significant proteinuria and nephrotic syndrome, however, constitute uncommon findings. We present four patients with AED documented histopathologically who developed nephrotic-range proteinuria. The mechanisms of proteinuria are discussed, and it is suggested that AED be considered in the differential diagnosis of nephrotic syndrome in elderly patients with serious vascular disease.
动脉粥样硬化栓塞性疾病（AED）多变的临床表现类似于累及肾脏的全身性疾病。在AED患者中，急性或慢性肾衰竭可自发出现，或在诱发事件后更常见。然而，显著蛋白尿和肾病综合征并不常见。我们报告了4例经组织病理学证实患有AED且出现肾病范围蛋白尿的患者。文中讨论了蛋白尿的机制，并建议在患有严重血管疾病的老年患者肾病综合征的鉴别诊断中考虑AED。
