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芝加哥儿童中的神经囊尾蚴病

Neurocysticercosis among children in Chicago.

作者信息

Rosenfeld E A, Byrd S E, Shulman S T

机构信息

Department of Pediatric Infectious Diseases, Northwestern University Medical School, Chicago, Illinois, USA.

出版信息

Clin Infect Dis. 1996 Aug;23(2):262-8. doi: 10.1093/clinids/23.2.262.

Abstract

Neurocysticercosis has been diagnosed increasingly in the United States as a consequence of increased immigration from and travel to areas of endemic cysticercosis. We report a retrospective series of 47 pediatric cases of neurocysticercosis in our large children's hospital in Chicago, which has a large immigrant population. Neurocysticercosis was diagnosed on the basis of any of the following three criteria: (1) surgical biopsy findings, (2) radiographic findings consistent with neurocysticercosis as well as diagnostic serum and/or cerebrospinal fluid titers, or (3) consistent radiographic findings and a compatible epidemiologic history (without diagnostic serological findings). Epidemiologic, clinical, laboratory, and radiographic data were analyzed. Neurocysticercosis is a relatively common cause of afebrile seizures in children who present to our emergency department in Chicago. Computed tomography and magnetic resonance imaging are both important modalities in evaluation of children with neurocysticercosis. Laboratory studies are neither sensitive for nor predictive of the diagnosis of neurocysticercosis. Therapy is well tolerated. The long-term prognosis for treated patients appears to be excellent.

摘要

由于来自囊尾蚴病流行地区的移民增加以及前往这些地区的旅行增多,神经囊尾蚴病在美国的诊断越来越多。我们报告了在芝加哥一家有大量移民人口的大型儿童医院对47例儿童神经囊尾蚴病病例进行的回顾性研究。神经囊尾蚴病根据以下三项标准中的任何一项进行诊断:(1)手术活检结果;(2)与神经囊尾蚴病一致的影像学结果以及诊断性血清和/或脑脊液滴度;或(3)一致的影像学结果和相符的流行病学史(无诊断性血清学结果)。对流行病学、临床、实验室和影像学数据进行了分析。神经囊尾蚴病是在芝加哥我们急诊科就诊的儿童中无热惊厥的相对常见原因。计算机断层扫描和磁共振成像都是评估儿童神经囊尾蚴病的重要手段。实验室检查对神经囊尾蚴病的诊断既不敏感也无预测性。治疗耐受性良好。接受治疗患者的长期预后似乎很好。

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