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神经囊尾蚴病:一种了解甚少的疾病。

Neurocysticercosis: a poorly understood disease.

作者信息

Vantomme M, Swartenbroekx R, Dhaen B, Peetermans W, Plets C, Demaerel P, Dom R, Robberecht W

机构信息

Department of Neurology, University Hospital Gasthuisberg, University of Leuven, Belgium.

出版信息

Acta Neurol Belg. 1995;95(1):23-8.

PMID:7725893
Abstract

A 22-year-old male patient of Indian origin presented with generalized seizures. Brain magnetic resonance imaging (MRI) showed two cystic lesions. Extensive screening only revealed positive skin tests for tuberculosis. Immunoassays for cysticerosis were negative in serum and cerebrospinal fluid. Biopsy of the temporal lesion revealed a cysticercus. Although neurocysticercosis is a common cause of seizures in patients from countries where cysticercosis is endemic, the diagnosis can be difficult in a patient with evidence of multiple infections or in whom serological evidence is lacking, as is illustrated by the present case. Furthermore, because the pathogenic factors determining the activity of the disease are poorly understood, its management represents a similar problem as it depends upon the activity of the disease as estimated by clinical, radiological and laboratory tests. The present case report illustrates these difficulties.

摘要

一名22岁的印度裔男性患者出现全身性癫痫发作。脑部磁共振成像(MRI)显示有两个囊性病变。广泛筛查仅发现结核菌素皮肤试验呈阳性。血清和脑脊液中囊尾蚴病免疫测定均为阴性。颞部病变活检显示有囊尾蚴。虽然神经囊尾蚴病是囊尾蚴病流行国家患者癫痫发作的常见原因,但对于有多种感染证据或缺乏血清学证据的患者,诊断可能会很困难,本病例即说明了这一点。此外,由于决定疾病活动的致病因素了解甚少,其治疗也存在类似问题,因为治疗取决于通过临床、放射学和实验室检查估计的疾病活动情况。本病例报告说明了这些困难。

相似文献

1
Neurocysticercosis: a poorly understood disease.神经囊尾蚴病:一种了解甚少的疾病。
Acta Neurol Belg. 1995;95(1):23-8.
2
[A case of solitary neurocysticercosis of unknown transmission route].[一例传播途径不明的孤立性神经囊尾蚴病病例]
No Shinkei Geka. 2002 Nov;30(11):1223-8.
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[Cerebral cysticercosis treated by albendazole: development of cerebral magnetic resonance imaging].阿苯达唑治疗脑囊尾蚴病:脑磁共振成像的发展
Rev Neurol (Paris). 1994 Oct;150(10):709-12.
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[Diagnosis of neurocysticercosis by immunoenzymatic staining technique (IEST) with frozen sections of Cysticercus cellulosae].[应用猪囊尾蚴冰冻切片免疫酶染色技术(IEST)诊断神经囊尾蚴病]
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1991;9(1):65-7.
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Cytologic diagnosis of neurocysticercosis. A case report.神经囊尾蚴病的细胞学诊断。病例报告。
Acta Cytol. 1994 Jan-Feb;38(1):87-9.
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[Grand-mal epilepsy as initial manifestation of a parenchymal neuro_cysticercosis].[大发作癫痫作为实质性神经囊尾蚴病的首发表现]
Schweiz Med Wochenschr. 1993 Jan 30;123(4):125-9.
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Magnetic resonance imaging of the brain for diagnosis of neurocysticercosis in a dog.用于诊断犬神经囊尾蚴病的脑部磁共振成像。
J Am Vet Med Assoc. 1996 Jun 1;208(11):1846-8.
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[Intraspinal manifestation of cysticercosis--Cysticercus racemosus. A case report and review of the literature].[囊尾蚴病的脊髓内表现——葡萄状囊尾蚴。一例病例报告及文献复习]
Nervenarzt. 1994 Aug;65(8):563-7.
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[Evaluation of ELISA and counterimmunoelectrophoresis in diagnosis of human neurocysticercosis in Chile].[酶联免疫吸附测定法和对流免疫电泳法在智利人体神经囊尾蚴病诊断中的评估]
Rev Med Chil. 1995 Dec;123(12):1461-6.
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Giant parenchymal cysticercosis with unusual imaging features.具有不寻常影像学特征的巨大实质性囊尾蚴病。
J Clin Neurosci. 2008 Dec;15(12):1404-6. doi: 10.1016/j.jocn.2007.09.026. Epub 2008 Oct 7.

引用本文的文献

1
Cysticercosis and taeniasis cases diagnosed at two referral medical institutions, Belgium, 1990 to 2015.1990 年至 2015 年在比利时两家转诊医疗机构诊断的囊尾蚴病和带绦虫病病例。
Euro Surveill. 2019 Aug;24(35). doi: 10.2807/1560-7917.ES.2019.24.35.1800589.
2
Epidemiology and management of cysticercosis and Taenia solium taeniasis in Europe, systematic review 1990-2011.欧洲囊虫病和猪带绦虫感染的流行病学和管理:1990-2011 年系统综述
PLoS One. 2013 Jul 29;8(7):e69537. doi: 10.1371/journal.pone.0069537. Print 2013.