Holstege G, Kuypers H G
Brain. 1977 Jun;100(2):239-64. doi: 10.1093/brain/100.2.239.
The local bulbar connections to the V, VII and XII motor nuclei in the cat have been studied by means of the anterograde fibre degeneration technique in combination with the Fink-Heimer silver impregnation procedure. For this purpose electrolytic lesions were made mainly in the reticular formation of the medulla oblongata and the pons. For control purposes also, extrabulbar lesions were made in the cervical cord and the upper brain-stem and in addition, primary afferent fibres were interrupted by section of the upper cervical and trigeminal roots. The findings indicated the existence of a lateral and a medial propriobulbar fibre system, the former of which projects to the motor nuclei mainly ipsilaterally, while the latter tends to project bilaterally. Since the cells of origin of the propriobulbar fibre systems are difficult to determine by means of the anterograde degeneration technique these systems have also been investigated by means of the labelled amino-acid tracing technique. The findings thus obtained are reported in the adjoining paper.
运用顺行性纤维变性技术并结合芬克 - 海默尔银浸染法，对猫中与三叉神经、面神经和舌下神经运动核的局部延髓连接进行了研究。为此，主要在延髓和脑桥的网状结构中制造电解损伤。作为对照，还在颈髓和上脑干制造了延髓外损伤，此外，通过切断颈上部和三叉神经根来中断初级传入纤维。研究结果表明存在一个外侧和一个内侧固有延髓纤维系统，前者主要同侧投射至运动核，而后者倾向于双侧投射。由于通过顺行性变性技术难以确定固有延髓纤维系统的起源细胞，因此也运用标记氨基酸追踪技术对这些系统进行了研究。由此获得的研究结果在相邻的论文中报告。
