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在高位去大脑猫中,长脊髓反射的符号反转取决于步周期的阶段。

Reversal of sign of long spinal reflexes dependent on the phase of the step cycle in the high decerebrate cat.

作者信息

Miller S, Ruit J B, Van der Meché F G

出版信息

Brain Res. 1977 Jun 17;128(3):447-59. doi: 10.1016/0006-8993(77)90170-6.

DOI:10.1016/0006-8993(77)90170-6
PMID:884493
Abstract

Reversal of the sign of long ascending and descending spinal reflexes dependent on the phase of the step cycle has been shown in the high decerebrate cat. Electrical stimuli were applied to the skin over the dorsum of the metacarpals and metatarsals and the effects were recorded in the corresponding hindlimb or forelimb of the same side. Stimulation generally evoked an increase in activity of flexor or extensor muscles shortly before, and during, activity of the muscle. Inhibition of a muscle occurred when its activity overlapped with the activity of an antagonist muscle. From the latencies it was concluded that at least the early components of the long reflex responses are due to spinal mechanisms. In the stimulated limb the activity of flexor and extensor muscles was also modulated in a phase dependent manner. No consistent long spinal responses to skin stimulation were obtained in high spinal cats during stepping. Electrical stimulation of cutaneous nerve trunks in decerebrate preparations during stepping gave variable though phase dependent long spinal reflex effects.

摘要

在高位去大脑猫中已显示,依赖于步周期阶段的长脊髓上升和下降反射的符号会发生反转。将电刺激施加于掌骨和跖骨背部的皮肤,并在同侧相应的后肢或前肢记录效应。刺激通常在肌肉活动之前不久和期间引起屈肌或伸肌活动增加。当一块肌肉的活动与拮抗肌的活动重叠时,该肌肉会受到抑制。从潜伏期可以得出结论,至少长反射反应的早期成分是由脊髓机制引起的。在受刺激的肢体中,屈肌和伸肌的活动也以相位依赖的方式受到调节。在高位脊髓猫行走过程中,未获得对皮肤刺激一致的长脊髓反应。在去大脑准备的动物行走过程中,对皮神经干进行电刺激产生了可变但相位依赖的长脊髓反射效应。

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