West P N, Hartmann A F, Weldon C S
Circulation. 1977 Sep;56(3 Suppl):II66-72.
Physical examination, chest roentgenography, phonocardiography, and right heart catheterization were used to evaluate the function of composite aortic homografts inserted as right ventricular outflow tracts in 13 patients 1.8 to 7 years previously. All homografts in these patients who were followed for 2 or more years demonstrated calcification of the aortic wall, but valve leaflets were spared. Moderate pulmonary insufficiency was present in eight patients with single cusp partial homografts, but was well tolerated in all. Homograft valve insufficiency was mild in five patients with complete homografts. No patient had an outflow tract gradient greater than 32 mm Hg. The average gradient was 18.5 +/- 2.7 (SEM) mm Hg. Abnormality of pulmonary blood flow was found in three patients and could be related to previous Waterston or Potts anastomoses. No late morbidity due to homograft degeneration has occurred and the long-term function of these conduits appears to be good.
对13例在1.8至7年前植入复合主动脉同种异体移植物作为右心室流出道的患者，采用体格检查、胸部X线摄影、心音图检查及右心导管检查来评估其功能。在这些随访2年或更长时间的患者中，所有同种异体移植物均显示主动脉壁钙化，但瓣叶未受累。8例使用单瓣部分同种异体移植物的患者存在中度肺动脉瓣关闭不全，但所有患者均能良好耐受。5例使用完整同种异体移植物的患者，同种异体移植物瓣膜关闭不全为轻度。无一例患者的流出道压差大于32 mmHg。平均压差为18.5±2.7（标准误）mmHg。3例患者发现肺血流异常，可能与既往的Waterston或Potts吻合术有关。尚未发生因同种异体移植物退变导致的晚期发病情况，这些管道的长期功能似乎良好。
