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近红外反射光谱法在药物分析控制中的应用:盐酸雷尼替丁片的生产

Application of near-infrared reflectance spectrometry to the analytical control of pharmaceuticals: ranitidine hydrochloride tablet production.

作者信息

Dreassi E, Ceramelli G, Corti P, Perruccio P L, Lonardi S

机构信息

Dipartimento Farmaco Chimico Tecnologico, Siena, Italy.

出版信息

Analyst. 1996 Feb;121(2):219-22. doi: 10.1039/an9962100219.

DOI:10.1039/an9962100219
PMID:8849039
Abstract

The possibility of applying near-infrared reflectance spectrometry to the control of the production cycle of ranitidine hydrochloride tablets was investigated. The results were good for the identification of ranitidine hydrochloride drug substance, mixtures for tablets, cores and coated tablets. The determination of the compound and of its water content also gave satisfactory results.

摘要

研究了将近红外反射光谱法应用于盐酸雷尼替丁片生产周期控制的可能性。该方法在鉴别盐酸雷尼替丁原料药、片剂混合物、片芯和包衣片方面效果良好。对该化合物及其水分含量的测定也得到了令人满意的结果。

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Application of near-infrared reflectance spectrometry to the analytical control of pharmaceuticals: ranitidine hydrochloride tablet production.近红外反射光谱法在药物分析控制中的应用:盐酸雷尼替丁片的生产
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Solid state assay of ranitidine HCl as a bulk drug and as active ingredient in tablets using DRIFT spectroscopy with artificial neural networks.采用带人工神经网络的漫反射红外傅里叶变换光谱法对原料药及片剂中作为活性成分的盐酸雷尼替丁进行固态分析。
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Quantitation of film coating on Zantac 75 mg tablets and Epivir HBV 100 mg tablets by ICP-AES.采用电感耦合等离子体发射光谱法(ICP-AES)对75毫克雷尼替丁片和100毫克拉米夫定片的薄膜包衣进行定量分析。
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引用本文的文献

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Compilation of a Near-Infrared Library for Construction of Quantitative Models of Oral Dosage Forms for Amoxicillin and Potassium Clavulanate.用于构建阿莫西林和克拉维酸钾口服剂型定量模型的近红外光谱库的编制
Front Chem. 2018 May 24;6:184. doi: 10.3389/fchem.2018.00184. eCollection 2018.
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Simultaneous determination of ranitidine and metronidazole in pharmaceutical formulations at poly(chromotrope 2B) modified activated glassy carbon electrodes.在聚(变色酸2B)修饰的活化玻碳电极上同时测定药物制剂中的雷尼替丁和甲硝唑。
J Food Drug Anal. 2014 Sep;22(3):345-349. doi: 10.1016/j.jfda.2013.09.050. Epub 2013 Dec 8.
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Solid state assay of ranitidine HCl as a bulk drug and as active ingredient in tablets using DRIFT spectroscopy with artificial neural networks.
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Pharm Res. 1999 Sep;16(9):1477-82. doi: 10.1023/a:1018975730945.