Dreassi E, Ceramelli G, Corti P, Perruccio P L, Lonardi S
Dipartimento Farmaco Chimico Tecnologico, Siena, Italy.
Analyst. 1996 Feb;121(2):219-22. doi: 10.1039/an9962100219.
The possibility of applying near-infrared reflectance spectrometry to the control of the production cycle of ranitidine hydrochloride tablets was investigated. The results were good for the identification of ranitidine hydrochloride drug substance, mixtures for tablets, cores and coated tablets. The determination of the compound and of its water content also gave satisfactory results.
研究了将近红外反射光谱法应用于盐酸雷尼替丁片生产周期控制的可能性。该方法在鉴别盐酸雷尼替丁原料药、片剂混合物、片芯和包衣片方面效果良好。对该化合物及其水分含量的测定也得到了令人满意的结果。