Toyama Y, Sumiya H, Fuse H, Shimazaki J
Department of Anatomy, School of Medicine, Chiba University, Japan.
Andrologia. 1996 Mar-Apr;28(2):81-7. doi: 10.1111/j.1439-0272.1996.tb02761.x.
Ejaculated spermatozoa from an infertile patient were examined by scanning and transmission electron microscopy. All spermatozoa had abnormalities in the tail region. The abnormalities were divided into three types: (a) spermatozoa with a spherical tail. The tail was larger than the head in volume. This type of abnormality accounted for about 60% of the population; (b) spermatozoa with a blunt tail. The tails were about 2 microns in diameter and about 7 microns in length. This type of abnormality accounted for about 30% of the population of an ejaculate; (c) spermatozoa without a tail. Some of these had only a rudimentary tail. About 10% of the population belonged to this type. In types A and B, all components of the tail, except for dynein arms, were observed, but they were severely disarranged. Biopsy specimens of the testes and of the nasal mucosa of this patient were also investigated. The testicular biopsy showed defects in manchette formation. Normal development of the manchette could not be observed. The nasal epithelium showed absence of the inner dynein arms in the cilia.
通过扫描电子显微镜和透射电子显微镜对一名不育患者射出的精子进行了检查。所有精子的尾部区域均存在异常。这些异常分为三种类型：（a）尾部呈球形的精子。尾部体积大于头部。这种异常类型约占总数的60%；（b）尾部钝圆的精子。尾部直径约2微米，长度约7微米。这种异常类型约占一次射精总数的30%；（c）无尾精子。其中一些只有残留的尾巴。约10%的总数属于这种类型。在A类和B类中，除动力蛋白臂外，尾部的所有成分均被观察到，但它们严重紊乱。还对该患者的睾丸和鼻黏膜活检标本进行了研究。睾丸活检显示在微管形成方面存在缺陷。未观察到微管的正常发育。鼻上皮显示纤毛中缺乏内动力蛋白臂。
