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产前诊断为泌尿系统疾病的新生儿

[Newborn infants diagnosed prenatally with uropathies].

作者信息

García Mérida M, Miguelez Lago C, Rius Díaz F, Galán Montenegro P, Galiano Duro E, Martínez Valverde A

机构信息

Sección de Urología Pediátrica, Hospital Materno-Infantil de Málaga.

出版信息

An Esp Pediatr. 1996 Jun;44(6):581-4.

PMID:8849103
Abstract

UNLABELLED

A clinical study of 111 newborns (NB) with prenatal diagnosis (PD) of urinary tract pathology was performed. The weight and size at birth, physical examination, incidence of uropathies, associated malformations and postnatal diagnostic studies were analyzed.

MATERIAL AND METHODS

All data corresponding to 111 neonates with PD of urinary tract pathology were submitted to the Student's t and Chi square tests and contingency tables.

RESULTS

Uropathies were more frequent in male NB (69%) and on the left side (2/1). Pyelocaliceal dilatation (PCD) was present in 46% of the patients. The mean weight and size was normal. However, NB with PCD had a mean weight of 249 grams below that observed in the remaining group (p = 0.016). Thirteen newborns (12%) had associated anomalies. An abdominal mass was present in 17 neonates with obstructive uropathies (15%). Serum urea and creatinine were normal in 101 neonates (91%).

SUMMARY

  1. PCD is the most frequent uropathy diagnosed prenatally. 2) The incidence of fetal uropathies, diagnosed prenatally, is higher in males. 3) The left side is more frequently involved. 4) The mean weight and size of NB with uropathies is normal. 5) The mean weight of NB with DCP is 249 grams lower than the rest of the group. 6) Serum urea and creatinine were found elevated only in severe bilateral obstructive uropathies.
摘要

未标注

对111例产前诊断为泌尿系统病变的新生儿进行了临床研究。分析了出生时的体重和尺寸、体格检查、泌尿系统疾病的发生率、相关畸形以及产后诊断研究情况。

材料与方法

将111例产前诊断为泌尿系统病变的新生儿的所有数据进行了t检验、卡方检验和列联表分析。

结果

泌尿系统疾病在男性新生儿中更为常见(69%),且左侧更为多见(2/1)。46%的患者存在肾盂肾盏扩张(PCD)。平均体重和尺寸正常。然而,患有PCD的新生儿平均体重比其余组低249克(p = 0.016)。13例新生儿(12%)有相关畸形。17例患有梗阻性泌尿系统疾病的新生儿(15%)可触及腹部肿块。101例新生儿(91%)的血清尿素和肌酐正常。

总结

1)PCD是产前诊断最常见的泌尿系统疾病。2)产前诊断的胎儿泌尿系统疾病在男性中发生率更高。3)左侧更常受累。4)患有泌尿系统疾病的新生儿平均体重和尺寸正常。5)患有DCP的新生儿平均体重比其余组低249克。6)仅在严重双侧梗阻性泌尿系统疾病中发现血清尿素和肌酐升高。

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