Yuasa N, Hattori T, Kobayashi Y, Miyata K, Fukata S, Kamei K, Kurumiya Y, Hayashi Y, Ebata T, Koide Y
Dept. of Surgery, Japanese Red Cross Nagoya First Hospital.
Gan To Kagaku Ryoho. 1995 Dec;22 Suppl 4:457-61.
Two cases with unresectable multiple liver metastases to both lobes (H3) from colon cancer, in which cases the life expectancy usually does not exceed 1 year, were treated with home hepatic arterial infusion chemotherapy employing implantable port system. They could live over one year with good performance status. Drug treatment consisted of the administration of carboplatin (CBDCA), 150 mg/body, given in a minute for one day and 5-fluorouracil (5-FU), 250 mg/body, given in a 5-hour intra-arterial infusion daily for 5 days. Cycles were administered every 2 weeks. Home hepatic arterial infusion chemotherapy using an implantable port system, which offers good local control of liver metastases, a high patient quality of life without the need for hospitalization, is suitable for treatment of unresectable liver metastases.
两例结肠癌导致双侧肝叶出现不可切除的多发肝转移（H3期）患者，通常情况下这类患者预期寿命不超过1年，采用植入式端口系统进行家庭肝动脉灌注化疗。他们能够存活超过一年且身体状况良好。药物治疗包括给予卡铂（CBDCA），150mg/人，一天内静脉推注一次，以及5-氟尿嘧啶（5-FU），250mg/人，每天经动脉5小时输注，共5天。每2周进行一个周期。使用植入式端口系统进行家庭肝动脉灌注化疗，对肝转移有良好的局部控制效果，患者无需住院且生活质量高，适用于不可切除肝转移的治疗。
