Kerensky R A, Franco E A, Bertolet B D, Thomas G, Wargovich T J
Section of Cardiology, University of Florida, Shands Hospital, Gainesville 32610-0277, USA.
Cathet Cardiovasc Diagn. 1996 Aug;38(4):410-4. doi: 10.1002/(SICI)1097-0304(199608)38:4<410::AID-CCD19>3.0.CO;2-I.
The presence of angiographic evidence of thrombus is generally thought to be a contraindication to coronary stent placement. This report describes four patients in whom angiographic thrombus was lysed using the Dispatch infusion catheter prior to coronary stenting. Urokinase was infused via the Dispatch catheter with resolution of angiographic evidence of thrombus in all cases. No complications were encountered using this technique, and all patients had excellent angiographic results after stenting. We conclude that lysis of intracoronary thrombus using the Dispatch infusion catheter is feasible and appears safe in this small study. Further trials are needed to determine if this technique reduces the acute stent thrombosis rate compared to other techniques for stent deployment in the presence of angiographic evidence of thrombus.
血管造影显示有血栓通常被认为是冠状动脉支架置入的禁忌症。本报告描述了4例患者,他们在冠状动脉支架置入术前使用Dispatch灌注导管溶解了血管造影显示的血栓。通过Dispatch导管注入尿激酶,所有病例血管造影显示的血栓均消失。使用该技术未出现并发症,所有患者支架置入术后血管造影结果均极佳。我们得出结论,在这项小型研究中,使用Dispatch灌注导管溶解冠状动脉内血栓是可行的,且似乎是安全的。需要进一步的试验来确定与在血管造影显示有血栓时进行支架置入的其他技术相比,该技术是否能降低急性支架血栓形成率。