Neugut A I, Lautenbach E, Abi-Rached B, Forde K A
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Am J Gastroenterol. 1996 Oct;91(10):2096-8.
The benefits of periodic colonoscopic surveillance after curative resection for colon cancer are controversial. We investigated the incidence, size, and time interval to the detection of recurrent adenomatous polyps in patients who have undergone resection of a colorectal cancer.
In this retrospective study, the records of 351 patients who underwent curative resection for colorectal carcinoma between 1967 and 1991 were reviewed. Sixty-one patients were excluded because of incomplete data.
Eighty-seven patients (30%) were found to have had at least one adenoma. Twelve patients had more than five adenomas. The median time to diagnosis was 24 months. Forty-six patients of the 87 (52.9%) had polyp recurrences within 2 yr after cancer resection.
This group of patients is at increased risk for the development of adenomatous polyps. Surveillance colonoscopy and polypectomy may reduce the incidence of metachronous colon cancer.
结肠癌根治性切除术后定期进行结肠镜监测的益处存在争议。我们调查了接受结直肠癌切除的患者中复发性腺瘤性息肉的发生率、大小及检测的时间间隔。
在这项回顾性研究中，我们回顾了1967年至1991年间351例行结直肠癌根治性切除患者的记录。61例患者因数据不完整被排除。
87例患者（30%）被发现至少有一个腺瘤。12例患者有五个以上腺瘤。诊断的中位时间为24个月。87例患者中有46例（52.9%）在癌症切除后2年内出现息肉复发。
该组患者发生腺瘤性息肉的风险增加。监测性结肠镜检查及息肉切除术可能会降低异时性结肠癌的发生率。
