Natsuume-Sakai S, Motonishi K, Migita S
Immunology. 1977 Jun;32(6):861-6.
The age-dependent change of the levels of five classes of immunoglobulin in mouse serum were investigated. Between 3 and 12 months after birth, the major IgG subclass of BALB/c was IgG1, while that of C57BL/6 was IgG2b. This difference was the same in the sera from hyperimmunized or germ-free animals.
研究了小鼠血清中五类免疫球蛋白水平的年龄依赖性变化。在出生后3至12个月之间,BALB/c小鼠的主要IgG亚类是IgG1,而C57BL/6小鼠的主要IgG亚类是IgG2b。在经高度免疫的动物或无菌动物的血清中,这种差异是相同的。