1例肾细胞癌术后接受γ干扰素治疗期间发生肾病综合征的病例。

A case of nephrotic syndrome developing during postoperative gamma interferon therapy for renal cell carcinoma.

作者信息

Tashiro M, Yokoyama K, Nakayama M, Yamada A, Ogura Y, Kawaguchi Y, Sakai O

机构信息

Kidney Center, Toranomon Hospital, Tokyo, Japan.

出版信息

Nephron. 1996;73(4):685-8. doi: 10.1159/000189160.

DOI:10.1159/000189160

PMID:8856271

Abstract

A 70-year-old man developed minimal-change nephrotic syndrome and acute interstitial nephritis while undergoing gamma interferon therapy following right nephrectomy for renal cell carcinoma. It appears that gamma interferon as well as renal cell carcinoma may have played a role as etiologic factors in this nephropathy. We report this extremely rare case of renal cell carcinoma complicated by minimal-change nephrotic syndrome and acute interstitial nephritis, and present a review of the literature.

摘要

一名70岁男性在因肾细胞癌行右肾切除术后接受γ干扰素治疗时，发生了微小病变型肾病综合征和急性间质性肾炎。看来γ干扰素以及肾细胞癌可能在这种肾病的病因中发挥了作用。我们报告了这例极其罕见的肾细胞癌合并微小病变型肾病综合征和急性间质性肾炎的病例，并对相关文献进行了综述。