关于由抗肾小球基底膜抗体介导的绵羊肾小球肾炎肾脏酸性洗脱液的研究。
Studies on acid eluates from kidneys of sheep with glomerulonephritis mediated by antibody to glomerular basement membrane.
作者信息
Batsford S R, Hardwicke J
出版信息
Int Arch Allergy Appl Immunol. 1977;54(5):475-8. doi: 10.1159/000231865.
PMID:885632
Abstract
Kidneys from six sheep having glomerulonephritis mediated by antibody to glomerular basement membrane (GBM) were extracted at acid pH. Each preparation was characterised using immunological techniques and the eluates contained between 3.6 and 13% anti-GBM antibody of IgG class. It appears that this low antibody content is due to the presence of contaminants, mainly serum proteins.
摘要
从六只患有由抗肾小球基底膜（GBM）抗体介导的肾小球肾炎的绵羊身上，在酸性pH值条件下提取肾脏。每种制剂都采用免疫学技术进行了表征，洗脱液中含有3.6%至13%的IgG类抗GBM抗体。这种低抗体含量似乎是由于存在污染物，主要是血清蛋白。
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