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Parathyroid hormone inhibitors. Design, synthesis, and biologic evaluation of hormone analogues.

作者信息

Rosenblatt M, Callahan E N, Mahaffey J E, Pont A, Potts J T

出版信息

J Biol Chem. 1977 Aug 25;252(16):5847-51.

PMID:885886
Abstract
摘要

相似文献

1
Parathyroid hormone inhibitors. Design, synthesis, and biologic evaluation of hormone analogues.甲状旁腺激素抑制剂。激素类似物的设计、合成及生物学评价。
J Biol Chem. 1977 Aug 25;252(16):5847-51.
2
Parathyroid hormone inhibitors. Determination of minimum sequence requirements.甲状旁腺激素抑制剂。最低序列要求的测定。
J Biol Chem. 1979 Jul 25;254(14):6496-8.
3
Analogues of parathyroid hormone containing D-amino acids: evaluation of biological activity and stability.
Biochemistry. 1980 Sep 2;19(18):4380-5. doi: 10.1021/bi00559a035.
4
Chemical and biological properties of synthetic, sulfur-free analogues of parathyroid hormone.
J Biol Chem. 1976 Jan 10;251(1):159-64.
5
Analogues of an in vitro parathyroid hormone inhibitor: modifications at the amino terminus.一种体外甲状旁腺激素抑制剂的类似物：氨基末端的修饰。
Calcif Tissue Int. 1981;33(2):153-7. doi: 10.1007/BF02409428.
6
Effects of calcium on a parathyroid hormone-sensitive adenylate cyclase inhibitor.
Biochem Biophys Res Commun. 1980 Jun 30;94(4):1227-32. doi: 10.1016/0006-291x(80)90550-1.
7
Relative sensitivity of kidney and bone to the amino-terminal fragment b-PTH (1-30) of native bovine parathyroid hormone: implications for assessment of bioactivity of parathyroid hormone fragments in vivo and in vitro.肾脏和骨骼对天然牛甲状旁腺激素氨基末端片段b-PTH(1 - 30)的相对敏感性：对体内和体外甲状旁腺激素片段生物活性评估的意义。
Calcif Tissue Int. 1983 Jul;35(4-5):520-5. doi: 10.1007/BF02405087.
8
Activation of bovine renal cortex membrane adenylyl cyclase by low concentrations of parathyroid hormone.低浓度甲状旁腺激素对牛肾皮质膜腺苷酸环化酶的激活作用。
Endocr Res Commun. 1980;7(2):87-98. doi: 10.1080/07435808009065962.
9
In vitro relative biological activities of (1--34)N-terminal synthetic fragments of human parathyroid hormone in the human renal cortical adenylate cyclase assay.人甲状旁腺激素（1-34）N端合成片段在人肾皮质腺苷酸环化酶分析中的体外相对生物学活性
FEBS Lett. 1978 Dec 1;96(1):79-82. doi: 10.1016/0014-5793(78)81066-7.
10
Analysis of the requirements for parathyroid hormone action in renal membranes with the use of inhibiting analogues.使用抑制类似物分析甲状旁腺激素在肾膜中的作用需求。
J Biol Chem. 1975 Apr 25;250(8):3199-203.

引用本文的文献

1
Small Molecule Inhibited Parathyroid Hormone Mediated cAMP Response by N-Terminal Peptide Binding.小分子通过N端肽结合抑制甲状旁腺激素介导的cAMP反应。
Sci Rep. 2016 Mar 2;6:22533. doi: 10.1038/srep22533.
2
International Union of Basic and Clinical Pharmacology. XCIII. The parathyroid hormone receptors--family B G protein-coupled receptors.国际基础与临床药理学联合会。XCIII。甲状旁腺激素受体——B族G蛋白偶联受体家族。
Pharmacol Rev. 2015;67(2):310-37. doi: 10.1124/pr.114.009464.
3
Mechanical stimulus alters conformation of type 1 parathyroid hormone receptor in bone cells.
机械刺激会改变骨细胞中1型甲状旁腺激素受体的构象。
Am J Physiol Cell Physiol. 2009 Jun;296(6):C1391-9. doi: 10.1152/ajpcell.00549.2008. Epub 2009 Apr 15.
4
The history of parathyroid hormone and its receptor: structure-based design of parathyroid hormone analogues.甲状旁腺激素及其受体的历史：基于结构的甲状旁腺激素类似物设计
Osteoporos Int. 1997;7 Suppl 3:S169-73. doi: 10.1007/BF03194366.
5
Effect of intrarenally infused parathyroid hormone-related protein on renal blood flow and glomerular filtration rate in the anaesthetized rat.肾内输注甲状旁腺激素相关蛋白对麻醉大鼠肾血流量和肾小球滤过率的影响。
Br J Pharmacol. 1996 Aug;118(8):1995-2000. doi: 10.1111/j.1476-5381.1996.tb15635.x.
6
A theoretical study of the structure of parathyroid hormone.甲状旁腺激素结构的理论研究
Proc Natl Acad Sci U S A. 1980 Jul;77(7):3791-5. doi: 10.1073/pnas.77.7.3791.
7
Human parathyroid hormone 1-34-mediated hypercalcemia in a rat model, and its inhibition by dichloromethane diphosphonate.人甲状旁腺激素1-34介导的大鼠模型高钙血症及其二氯甲烷二膦酸盐抑制作用
Calcif Tissue Int. 1981;33(6):649-54. doi: 10.1007/BF02409503.
8
Relative sensitivity of kidney and bone to the amino-terminal fragment b-PTH (1-30) of native bovine parathyroid hormone: implications for assessment of bioactivity of parathyroid hormone fragments in vivo and in vitro.肾脏和骨骼对天然牛甲状旁腺激素氨基末端片段b-PTH(1 - 30)的相对敏感性：对体内和体外甲状旁腺激素片段生物活性评估的意义。
Calcif Tissue Int. 1983 Jul;35(4-5):520-5. doi: 10.1007/BF02405087.
9
Action of bPTH and bPTH fragments on embryonic bone in vitro: dissociation of the cyclic AMP and bone resorbing response.bPTH及bPTH片段对体外培养胚胎骨的作用：环磷酸腺苷反应与骨吸收反应的分离
Calcif Tissue Int. 1983;35(1):70-7. doi: 10.1007/BF02405009.
10
Identification of adenylate cyclase-stimulating activity and cytochemical glucose-6-phosphate dehydrogenase-stimulating activity in extracts of tumors from patients with humoral hypercalcemia of malignancy.在恶性肿瘤所致体液性高钙血症患者肿瘤提取物中鉴定腺苷酸环化酶刺激活性和细胞化学葡萄糖-6-磷酸脱氢酶刺激活性。
Proc Natl Acad Sci U S A. 1983 Mar;80(5):1454-8. doi: 10.1073/pnas.80.5.1454.