Muller-Hagedorn S, Forges T, Kutter D, Conrad R
Department des Sciences, Centre Universitaire de Luxembourg, Luxembourg.
Acta Clin Belg. 1996;51(4):275-8. doi: 10.1080/22953337.1996.11718522.
Complete and permanent absence of peripheral eosinophilic granulocytes was observed in a patient also presenting with total myeloperoxidase deficiency. The anomaly was suspected because of complete absence of the eosinophilic cluster in the display of a H*3 Technicon hematological automate and was confirmed by traditional staining of more than 100,000 leukocytes. A severe infectious problem during adolescence could be related to MPO deficiency in this patient. No specific disorder attributable to aneosinophilia was however observed subsequently.
在一名同时患有全髓过氧化物酶缺乏症的患者中,观察到外周嗜酸性粒细胞完全且永久性缺失。由于在H*3 Technicon血液学自动分析仪的检测结果中完全没有嗜酸性粒细胞簇,怀疑存在这种异常情况,并通过对超过100,000个白细胞进行传统染色得以证实。该患者青春期期间的严重感染问题可能与髓过氧化物酶缺乏有关。然而,随后未观察到可归因于嗜酸性粒细胞缺乏的特定病症。