Cohen M P, Jasti K, Rye D L
J Clin Endocrinol Metab. 1977 Aug;45(2):236-9. doi: 10.1210/jcem-45-2-236.
Somatomedin activity in sera from twelve insulin-dependent diabetics was measured by the chick embryo cartilage assay system. All patients required insulin for control of hyperglycemia, and had been continuously treated with exogenous insulin for 3 to 25 years. Mean fasting somatomedin activity was elevated in this group of diabetics, and activity did not correlate with the simultaneous blood glucose concentrations. No significant differences were demonstrable between levels in diabetics with and without retinopathy or in patients with and without proteinuria.
通过鸡胚软骨检测系统测定了12名胰岛素依赖型糖尿病患者血清中的生长调节素活性。所有患者均需胰岛素来控制高血糖，且已接受外源性胰岛素持续治疗3至25年。该组糖尿病患者的平均空腹生长调节素活性升高，且活性与同时测得的血糖浓度无关。有视网膜病变和无视网膜病变的糖尿病患者之间，以及有蛋白尿和无蛋白尿的患者之间，生长调节素水平均无显著差异。
